Process Chemistry Senior Principal Scientist

The successful candidate will possess a deep knowledge of process chemistry skills for the development of synthetic routes, with knowledge and experience in early and mid to late-phase development and delivering drug substance under tight timelines. They will have a strong interest in laboratory work and will be key to driving the development of safe and scalable chemistry. They will spearhead the advancement of Vertex’s early phase portfolio through personal laboratory effort as well as overseeing internal and external resources. They will leverage additional Vertex resources (high-throughput experimentation, engineering and material sciences, process safety, analytical, etc.) to assist in identifying and improving reaction conditions for key transformations. The successful candidate will participate in cross-functional teams requiring good communication skills. The successful candidate will have accountability for creating and developing a synthetic route to deliver active pharmaceutical ingredients (APIs) within a specification range fit for the phase of development and delivering the technology and materials to enable candidate progression through development. The Sr. Principal Scientist Process Chemistry will lead / participate in cross-functional technical teams within their field of expertise. They will also be responsible for mentoring internal process chemistry scientists and promote the department through publications in peer reviewed journals and participation in external conferences.

• Key Responsibilities Include :
• Work with Pharm Sci team to develop project strategy, timelines, and leverage technical expertise and planning ability.
• Knowledge and Skills :
• Ability to communicate difficult concepts, ideas, and solutions
• Other duties as defined
• Education and Experience :
• Bachelor's degree and 11+ years of experience or a Master's degree and 9+ years of experience or a PhD and 6-8+ years of experience in the pharmaceutical industry#LI-BS1Knowledge and understanding regulatory factors and maintaining expert knowledge in chemistryThe range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.In this
• On-Site
• designated role, you will work
• five days per week on-site
• with ad hoc flexibility.

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