Senior / Principal Scientist, Translational AI Lab (TRAIL)

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

The Translational AI Lab (TRAIL) is a division within the newly formed AI Biology & Translation (AIBT) department in gRED’s Computational Sciences Center of Excellence (CS-CoE). TRAIL’s mission is to harness the power of AI to unlock new biological insights by translating foundational models into applied impact—driving discovery in target identification, disease understanding, and therapeutic exploration. As a Senior / Principal Scientist, you will lead scientific initiatives that bridge cutting-edge AI capabilities and real-world biological applications. This role is ideal for a scientist with a record of scientific excellence, cross-disciplinary fluency, and deep translational curiosity.

You’ll work in close partnership with :

• BRAID (Biology Research AI Development), our internal AI model development team,
• Computational Biology & Medicine (CBM) and therapeutic area scientists,
• Experimental and data-generating partners across Genentech R&D (i.e. Research, Translational Medicine, Cellular & Tissue Genomics etc).

Key Responsibilities

Who you are

Senior Scientist

Principal Scientist

About AIBT and the CS-CoE

AI Biology & Translation (AIBT) brings together model development (via BRAID) and model application (via TRAIL) under one translationally focused department to drive AI impact across Genentech’s R&D. Situated within the Computational Sciences Center of Excellence (CS-CoE), AIBT plays a central role in shaping the future of drug discovery through a unique combination of foundational AI and applied biology.

Relocation benefits are available for this job posting.

The expected salary range for this position, based on the primary location of California, is (Senior Scientist : $167,400 - 310,800) and (Principal Scientist : $194,000 - 360,400). Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company\'s policy prohibits unlawful discrimination, including but not limited to discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by stating Accommodations for Applicants.

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