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Director of Analytical Development

Director of Analytical Development

AntheiaMenlo Park, CA, US
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Director of Analytical Development

Antheia is a science and technology company developing next generation plant-inspired medicines. Applying synthetic biology, genomics, bioinformatics, data science, and fermentation, we harness the most beneficial molecules from plants to create active pharmaceutical ingredients in more controlled and economical ways. We are a close-knit team inspired by the possibilities of delivering transformative technologies and breakthrough science to change the course of medicine. We value our people as our most important resource and are always looking for talented individuals who can make valuable contributions to our efforts.

The employee will be responsible for managing and leading the AD department and all analytical instrumentation including HPLC, GC-MS, IC, LC-MS / MS, and RapidFire MS. A successful employee will be a strong communicator, effective problem solver, and able to work efficiently in a fast-paced, dynamic environment characteristic of a start-up. The candidate will be capable of working collaboratively with the R&D teams to ensure the AD capacities meet the needs of the scientific departments by setting and effectively communicating realistic timelines. As the AD department provides support to all R&D teams, a strong operational background and vision is critical for this position. Responsibilities include :

  • Work with senior management and leadership teams to develop a strategic vision for Antheia's AD capabilities and workflow.
  • Hire and ensure training of key staff to support both the operational and R&D sides of AD.
  • Interface with directors and research staff in other departments to identify new analytical method development needs and prioritize resources based on corporate and department goals.
  • Advocate for the individual members of the AD team, ensuring they achieve their own personal development goals.
  • Establish workflows and timelines for phase-appropriate analytical method development and provide ongoing technical support and leadership.
  • Work with the R&D teams to ensure methods are fit-for-purpose and continue to monitor performance and data quality with real samples.
  • Develop a strong operational core to meet the needs of all R&D departments and organize and coordinate efforts to ensure streamlined use of analytical instrumentation and personnel.
  • Work with data science department to develop and improve request systems for analytical samples and ensure robust and streamlined integration of data into data management systems and visualization tools.
  • Seek and qualify new technologies and techniques that will further advance / enable project goals, including identification of contract research labs.
  • Develop clear SOPs that can be used internally and shared with partners to support tech transfer activities.
  • Partner with QC to identify opportunities for improving existing test methods, ensuring they meet regulatory standards and are optimized for efficiency, accuracy, and cost-effectiveness.
  • Support the transfer of analytical methods from Analytical Development to QC, including review of transfer protocols and troubleshooting to ensure smooth adoption and compliance.
  • Collaborate with the QC team on method refinement, qualification, and lifecycle management to ensure methods are robust, reproducible, and aligned with ICH Q2(R2) / Q14 requirements.
  • Responsible for purchasing and maintenance of all analytical equipment.
  • Perform other duties as assigned.

Qualifications / Experience :

  • Ph.D. in Chemistry, Analytical Chemistry, or equivalent discipline. 10+ years of experience.
  • Strong technical knowledge of analytical equipment and methods, especially mass spectrometry (including high resolution MS) for small molecules.
  • Experience with HTP sample preparation, including using automation.
  • Experience with additional analytical methods such as ion chromatography, size exclusion chromatography, Karl Fischer analysis is a plus.
  • Demonstrated ability to build and lead teams.
  • (Bonus Experience) Understanding and / or familiar with of ICH Q2(R2) and ICH Q14 for analytical procedure development and validation of analytical procedures.
  • (Bonus Experience) Understanding and / or familiar with of ICH Q6A / Q6B for specifications for biotechnological products and acceptance criteria for small molecules.
  • Strong background in operations and organizing analytical services in support of R&D teams.
  • Additional Information : Full-time base salary range of $190,000 $220,000 plus an annual bonus potential and equity opportunities.

    Antheia doesn't discriminate based on age, race, ethnicity, national origin, religion, gender, sexual orientation, disability, medical history, and other non-merit characteristics.

    Antheia offers a comprehensive total rewards package for full-time employees. Part-time (

  • Comprehensive compensation package, which includes annual bonus potential and equity opportunities
  • Paid time off, in addition to company-observed holidays
  • Excellent medical, dental, and vision insurance
  • 401(k) retirement savings plan
  • Free access to the Menlo Park Labs Gym
  • Menlo Park Labs free shuttle service to CalTrain, BART Station, and SF
  • Antheia is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Antheia prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws. Legal authorization to work in the United States is required.

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    Director Of Development • Menlo Park, CA, US

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