Senior Research Associate, MOA of Cancer Therapeutics, Disease Mechanism Research

Senior Research Associate, MOA of Cancer Therapeutics, Disease Mechanism Research

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians.  If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com .

This position is based in South San Francisco, CA.  Remote work from certain states may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.

Purpose and Scope :

The Disease Mechanism Research team at Astellas West Coast Innovation Center is looking for a passionate and driven individual to join our fast-paced team. This position will support oncology disease mechanism research with a dynamic drug discovery environment. The scientist will apply deep expertise in cell culture and immuno-oncology to advance experimental strategies and data generation. This role will contribute towards efforts of understanding drug and disease mechanisms of action and will require collaboration with internal and external project teams to drive progress towards research milestones. This position will be located on site in South San Francisco.

Essential Job Responsibilities :

• Perform cell-based assays including cytotoxicity assay and flow cytometry to support the cancer biology research
• Establishing cell lines from primary tumor tissue
• Conduct molecular and biochemistry assays including Western Blot, ELISA, DNA / RNA extraction, PCR and qPCR
• Independently design and execute experiments to generate high-quality and reproducible data to evaluate mechanisms of resistance and action of therapeutic molecules
• Analyze experimental results using tools such as GraphPad Prism and FlowJo
• Maintain accurate detailed, and well-organized electronic lab notebooks and experimental records
• Collaborate and communicate effectively with team members and cross-functional groups to support project goals