Bioinformatics Analyst III

Title : Bioinformatics Analyst III

Duration : 1-2 months

Location : Cambridge, MA

Top 3 - 5 Skills Needed :

1. Implementing, training AI / ML models

2. Data pre-processing for AI compatibility

3. Domain knowledge of bioinformatics

4. Experience working with single cell and spatial data (transcriptomics, proteomics, epigenomics etc.)

5. Ability to communicate results clearly

Job Description :

The successful candidate will work closely with stakeholders across the IPSI (Immune Profiling & Systems Immunology in Immunology Discovery) organization to advance the Single-Cell Fibroblast Atlas initiative. The role will focus on applying AI / ML and advanced computational methods to large-scale single-cell transcriptomic, proteomics and spatial etc. datasets to define fibroblast states, map tissue-specific niches, and uncover their roles in health and disease.

Key Responsibilities

• Curate, harmonize, and analyze large-scale single-cell and spatial omics datasets (internal and public) with emphasis on fibroblast biology.
• Develop and optimize predictive AI / ML models to classify fibroblast states, identify regulatory networks, and generate disease-relevant insights.
• Integrate multi-modal data (scRNA-seq, spatial etc.) to construct a comprehensive fibroblast atlas.
• Collaborate with other stakeholders.

Impact

By building the Fibroblast Atlas, the candidate will enable target discovery while driving cross-functional projects at the interface of data science, immunology, and translational medicine impacting the portfolio.

Key Responsibilities

Qualifications :

Preferred Technical Skills :

Additional Technical Skills (a plus) :