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Scientist - Ligand Binding Assays (LBA)

Scientist - Ligand Binding Assays (LBA)

Yoh, A Day & Zimmermann CompanySwiftwater, PA, US
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Job Description

Scientist - Ligand Binding Assays (LBA)

Primary Duties : The Scientist for the LBA team will design, develop, qualify, validate, and implement ligand-binding immunoassays that support clinical endpoints across our client's vaccine portfolio. The role demands expertise in methods and technologies that include ELISA, RIA, Luminex, Ortho VITROS, ECL and automated platforms. The candidate will also be expected to provide mentorship and effectively supervise and train lab personnel to perform assigned tasks while ensuring applicable compliance and regulatory agency standards are met. The candidate will serve as key resource as expert technical representation within its organization and on multidisciplinary teams. This is a laboratory-based role and the candidate is expected to spent high percent time in lab.

Responsibilities include but are not limited to :

  • Provide numerical data if available to describe the size of the job, or its impact on the business. Use annual figures and specify currency. Figures should include budgetary responsibility, purchasing authority, resources available. Highlight the key decisions made in this job. Outline the sphere of the job, such as whether the accountabilities are global, country specific, or function specific.
  • Limited budgetary responsibilities. Sphere of job is function specific with some global accountability depending on project assignments.

Responsibilities Breakdown :

80% :

Scientific Operations and Management

  • Evaluate new technologies and automation to enhance throughput, precision, accuracy, and overall quality for clinical studies.
  • Interpret, summarize and report complex data sets with clear and concise oral and written communications.
  • Serve as an internal subject matter expert on developed assays and demonstrate the ability to educate, train or mentor other team members.
  • Perform / support activities to ensure test method life cycle management (documentation, method suitability / trending, maintenance, etc.).
  • Support completion of analytical deliverables to meet project milestones.
  • Lead and assist in the evaluation of new technologies and automation improvements to support analytical expertise as required.
  • Works with internal and external partners in support of collaborative projects.
  • 10% :

    Laboratory Operations

  • Under direction of management, plans and oversees the day-to-day operations and general activities associated with one or more laboratories / projects.
  • Ensures laboratory resources (materials / reagents / equipment / facilities) are maintained to meet assigned objectives.
  • Support a quality and compliant testing environment (laboratories, equipment, reagents, training and documentation, methods, personnel).
  • Maintain alignment of processes and procedures. Share best practices within team / platform.
  • 5%

    Personnel Supervision and Management

  • Oversees operational activities of staff working in the laboratory
  • Provides guidance and expert advice to staff on technical issues, safety procedures and regulatory compliance matters within the laboratory.  Monitors operations to ensure compliance.
  • Ensures that new employees are appropriately trained / on-boarded and familiar with laboratory operational requirements.
  • Provide guidance and training for complex molecular assays.
  • 5%

    Regulatory / Quality Management

  • Ensures adherence to all applicable quality, corporate, safety, and regulatory requirements.
  • May serve as Subject matter Expert (SME) as required.
  • Support departmental quality by ensuring adequate support for documentation, investigation, and closure of quality items including change controls, deviations, and CAPAs.
  • Education and Experience Requirements :

  • Specialized degree in biological sciences from an accredited University.
  • B.Sc. + 6yr experience.
  • M.Sc. + 3yr experience.
  • PhD + 1yr experience.
  • Demonstrated previous experience with developing and / or applying ligand binding immunoassays to detect and quantify analytes in biological or other complex samples, as evidenced by scientific publications and presentations at scientific meetings.
  • Ability to work with viruses, bacteria and potentially infectious samples from humans (BSL-2 or BSL-2+).
  • Lead, mentor and train lab staff.
  • Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.
  • Excellent technical, critical thinking and communication (oral and written) skills with ability to manage projects and resolve technical problems independently and also work effectively within cross-functional teams.
  • Be a highly motivated team player with the ability to interact effectively within a multi-disciplinary team.
  • Key Skills, Abilities, and Competencies :

  • Demonstrated previous experience with developing and / or applying ligand binding immunoassays to detect and quantify analytes in biological or other complex samples, as evidenced by scientific publications and presentations at scientific meetings.
  • Ability to work with viruses, bacteria and potentially infectious samples from humans (BSL-2 or BSL-2+).
  • Lead, mentor and train lab staff.
  • Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.
  • Excellent technical, critical thinking and communication (oral and written) skills with ability to manage projects and resolve technical problems independently and also work effectively within cross-functional teams.
  • Be a highly motivated team player with the ability to interact effectively within a multi-disciplinary team.
  • Complexity and Problem Solving :

  • To function as technical lead, establish and implement new and novel immunoassays and technologies to support clinical studiesaimed at advancing vaccines for infectious diseases.
  • Estimated Min Rate : $35.90

    Estimated Max Rate : $51.29

    What’s In It for You?

    We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include :

  • Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
  • Health Savings Account (HSA) (for employees working 20+ hours per week)
  • Life & Disability Insurance (for employees working 20+ hours per week)
  • MetLife Voluntary Benefits
  • Employee Assistance Program (EAP)
  • 401K Retirement Savings Plan
  • Direct Deposit & weekly epayroll
  • Referral Bonus Programs
  • Certification and training opportunities
  • Note : Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.

    Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

    Visit -with-disabilities to contact us if you are an individual with a disability and require accommodation in the application process.

    For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

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