Associate Director, Value Demonstration

Alnylam seeks a motivated and skilled Associate Director of Value Demonstration to join its Value Evidence & Strategy (VESt) group. Working under the direction of a project lead, the successful candidate will focus on the execution of specific RWE research projects from conception through completion, using a variety of real-world data (RWD) sources. This role involves developing study protocols and analysis plans, managing external vendors, and interpreting study results to generate evidence supporting our therapeutic products. The AD does not need to have programming skills but should be able to provide knowledgeable oversight to programming teams and vendors.

This is an hybrid position primarily located at the Cambridge, MA site.

Responsibilities

• Project Execution : Under the guidance of a project lead, translate research ideas and objectives into detailed study protocols, statistical analysis plans, and technical specifications for studies using diverse real-world data (RWD) sources, such as claims data, electronic health records (EHRs), and patient registries.
• Vendor Management : Oversee and provide informed oversight to vendors and contract research organizations (CROs) conducting RWE studies, ensuring timely delivery, adherence to protocols, and scientific rigor.
• Cross-Functional Collaboration : Partner with internal cross-functional teams, including Medical Affairs, VESt Health Economics and Outcomes Research (HEOR), and Epidemiology, to receive guidance on study design, statistical methodologies, and project deliverables.
• Results Interpretation : Interpret, summarize, and present study results to technical and non-technical audiences via study tables, presentations, and reports, ensuring accurate and clear communication of findings.
• Methodological Oversight : Provide informed oversight on methodological approaches used by internal and external programmers, reviewing programming specifications and analytic outputs to ensure quality and validity.
• Quality Assurance : Support cross-functional initiatives to refine internal workflows, procedures, and best practices for RWE activities and ensure studies meet internal quality standards.

Requirements

Preferred Qualifications

U.S. Pay Range

$170,300.00 - $230,300.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website : https : / / www.alnylam.com / careers

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values : fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.