Talent.com
Director, Country Operations Management
Director, Country Operations ManagementAstraZeneca • Boston, MA, US
Director, Country Operations Management

Director, Country Operations Management

AstraZeneca • Boston, MA, US
job_description.job_card.variable_days_ago
serp_jobs.job_preview.job_type
  • serp_jobs.job_card.full_time
job_description.job_card.job_description

Director, Country Operations Management (DCOM)

Location : Boston, Seaport

Hybrid : 60% onsite

The Director, Country Operations Management (DCOM) is a member of the local study delivery leadership team accountable for execution of interventional Phase 2 and 3 clinical trials within an assigned Therapy Area. This role is fully accountable for delivering all operational trial milestoneson time, with quality, and in compliance with ICH-GCP, SOPs, and US regulations.

This role combines strategic project leadership with direct line management of a team of 810, ensuring optimized resource planning, cross-functional collaboration, and high team performance across complex clinical programs. This role offers the opportunity to lead impactful clinical programs while developing and empowering a team of clinical professionals. The DCOM plays a critical role in local study delivery, ensuring excellence in both people leadership and operational delivery.

Key Responsibilities

People Leadership & Team Development

  • Lead, manage, and develop a high-performing team of 810 direct reports, including local study project managers and clinical study administrators
  • Drive performance management, training, coaching, and career development aligned with business needs and individual development goals
  • Manage workload allocation, resource optimization, and team succession planning in partnership with senior leadership and HR
  • Provide input on compensation, bonus proposals, and promotions in collaboration with HR and the US Head of County Operations

End-to-End Study Oversight

  • Oversee the execution of Phase 2 & 3 interventional studies across site feasibility, start-up, recruitment, maintenance, and close-out
  • Ensure trial milestones and deliverables are achieved with high quality and within agreed timelines
  • Robust oversight of site performance, study documentation, eTMF completeness, and regulatory compliance

    • Project Management & Operational Delivery

  • Monitor key performance indicators (KPIs) and operational metrics across assigned TA to ensure quality and consistency
  • Identify and mitigate operational risks, issues, and roadblocks in collaboration with global study teams and local partners
  • Drive process improvements, standardization, and adoption of country-level best practices
  • Lead transformation and change initiatives to strengthen the local Clinical Operations Management (COM) function

    • Stakeholder & Vendor Engagement

  • Collaborate cross-functionally with local Medical Affairs, Regulatory, Legal, Development Quality, and other internal partners
  • Manage external vendor performance, including CROs and FSPs, ensuring alignment with clinical objectives and standards
  • Maintain effective communication pathways with global study teams, Start-Up Managers, Site Partnership functions, and CRA managers
  • Represent the local TA perspective in broader country strategy discussions

    • Qualifications

  • Bachelor's degree in life sciences or related field (Master's or PhD preferred)
  • Minimum 7 years of experience in clinical research, including significant exposure to Phase 2 / 3 interventional trials
  • At least 3 years of direct people management experience in clinical operations
  • Demonstrated success managing cross-functional and vendor relationships
  • Strong working knowledge of ICH-GCP, global regulatory requirements, and local trial execution environments
  • Proven ability to drive delivery across multiple concurrent studies in a fast-paced, matrixed environment
  • Excellent communication, influencing, and stakeholder management skills

    • Preferred Qualifications

  • Previous experience as a field CRA
  • Experience in rare or ultra-rare disease trials, including pediatric or complex patient populations
  • Experience with U.S.-based studies and site management
  • Solid background in inspection readiness, risk mitigation, and continuous improvement
    • serp_jobs.job_alerts.create_a_job

    Management Management • Boston, MA, US

    Job_description.internal_linking.related_jobs
    Director of Commercial Operations

    Director of Commercial Operations

    Vizgen Inc • Cambridge, MA, US
    serp_jobs.job_card.full_time
    Location : Cambridge, MA (Hybrid) About Vizgen.Vizgen is revolutionizing genomics with cutting-edge technologies that reveal the spatial organization of genes within tissues.By harnessing the power ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director, Strategy & Operations

    Director, Strategy & Operations

    EverQuote • Cambridge, MA, US
    serp_jobs.job_card.full_time
    Join EverQuote as our next Director of Strategy & Operations and lead critical growth and transformation programs that directly shape our future. This highly visible role is designed to develop ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director of Commercial Operations

    Director of Commercial Operations

    Fresenius Medical Care • Lawrence, MA, US
    serp_jobs.job_card.full_time
    Director Of Commercial Operations.The Director of Commercial Operations is responsible for partnering with sales leadership and cross-functional teams to translate complex data into impactful selli...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Global Client Operations, Managing Director

    Global Client Operations, Managing Director

    State Street • Quincy, MA, US
    serp_jobs.job_card.full_time
    Managing Director, Global Client Operations.We are seeking a dynamic and strategic Managing Director to lead our global Client Operations function. This executive will be responsible for overseeing ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Managing Director, Strategy & Operations

    Managing Director, Strategy & Operations

    Kids In Tech • Lowell, MA, US
    serp_jobs.job_card.full_time
    Kids in Tech equips young people with the skills and confidence to succeed in a technology-driven world.Through engaging, hands-on STEAM programs, we help close the digital divide and inspire the n...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director of Development Operations

    Director of Development Operations

    Scholar Rock • Cambridge, MA, US
    serp_jobs.job_card.full_time
    Scholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biolo...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Super Pollutant Program Director

    Super Pollutant Program Director

    Cascade Climate • Boston, MA, US
    serp_jobs.job_card.full_time
    Super Pollutant Program Director.Join Cascade Climate, a global nonprofit propelling high-potential climate solutions from the margins to the mainstream. The climate crisis has outpaced our response...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director of Operations

    Director of Operations

    First Watch Restaurants • Boston, MA, US
    serp_jobs.job_card.full_time
    The Director of Operations is responsible for supporting the mission, vision, and values of First Watch through all that he / she does in their role every day. The DOs primary purpose is to develop Ge...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    National Account Director

    National Account Director

    Aramark Corporation • Boston, MA, United States
    serp_jobs.job_card.full_time
    The National Account Director is responsible for the day-to-day responsibilities of the entire account coordinated with the National client. Acts as the national-level, single point of contact and p...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director / Senior Director, Asset Management

    Director / Senior Director, Asset Management

    The RMR Group • Newton, MA, US
    serp_jobs.job_card.full_time
    Director / Senior Director, Asset Management.The Director / Senior Director, Asset Management supports the RMR Group's objectives of enhancing asset value for its managed REIT, Diversified HealthCare T...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Global Operations Director

    Global Operations Director

    Amphenol TCS • Nashua, NH, US
    serp_jobs.job_card.full_time
    Amphenol High Speed Products Group is the market leader for high speed, high bandwidth electrical connectors for the Telecom / Datacom market (Mobile Networks, Storage, Servers, Routers, Switches, et...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director of Partnerships

    Director of Partnerships

    Later • Boston, MA, US
    serp_jobs.job_card.permanent
    Later is the enterprise leader in social media and influencer marketing software, services, and data, trusted by leading brands and agencies worldwide. Following our acquisition of Mavely, the Every...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    GLOBAL OPERATIONS DIRECTOR

    GLOBAL OPERATIONS DIRECTOR

    Boston IVF • Stoneham, MA, US
    serp_jobs.job_card.full_time
    Global Chief Transformation Officer.The Global Director of Operations is a strategic enabler who partners with IVIRMA’s regional COOs and CEOs to elevate operational capabilities and drive pe...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director, Operational Excellence

    Director, Operational Excellence

    Apellis Pharmaceuticals, Inc. • Waltham, MA, United States
    serp_jobs.job_card.full_time
    The Director of Operational Excellence plays a pivotal role in shaping how the Technical Operations organization executes its work-through structured project delivery, standardized methodologies, a...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director of Operations

    Director of Operations

    Janji • Somerville, MA, US
    serp_jobs.job_card.full_time
    Somerville, MA (Hybrid – 2+ days / week in office).Janji makes the best gear for the longest distances — apparel built to inspire exploration and connect the global running community.Base...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Senior Director, Operations

    Senior Director, Operations

    QinetiQ US • Franklin, MA, US
    serp_jobs.job_card.full_time
    QinetiQ is seeking a Senior Director of Operations to drive operational departments in an industrial environment to align with customer and corporate imperatives. The Senior Director of Operations w...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director of Corporate Operations

    Director of Corporate Operations

    Drug Hunter • Boston, MA, US
    serp_jobs.job_card.full_time
    Drug Hunter is the trusted knowledge platform for drug discovery teams.We help scientists and R&D leaders move faster and more confidently by curating the most relevant insights and disclosures...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director, Operational Excellence

    Director, Operational Excellence

    Apellis • Waltham, MA, US
    serp_jobs.job_card.full_time
    The Director of Operational Excellence plays a pivotal role in shaping how the Technical Operations organization executes its work—through structured project delivery, standardized methodolog...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted