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Manufacturing Technician 4 - ADC Manufacturing

Manufacturing Technician 4 - ADC Manufacturing

Merck GroupMO, US
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Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role :

Join our St. Louis Cherokee facility at MilliporeSigma, a leading contract development and manufacturing organization (CDMO) and a recognized Center of Excellence for antibody-drug conjugate (ADC) manufacturing. We are seeking passionate and enthusiastic professionals to contribute to our innovative bioconjugate production, leveraging over 35 years of expertise in the field. As a vital part of our dedicated team, you will play a key role in delivering high-quality ADCs that improve the quality of life for patients suffering from cancer and other debilitating diseases. With our state-of-the-art technologies and commitment to excellence, you will ensure the highest standards of quality and compliance in our ADC manufacturing processes.

As a Manufacturing Technician 4 – Rotating Shift, you will be expected to safely execute tasks, develop new approaches, and perform support operations in a cGMP regulated environment for the support of API (Active Pharmaceutical Ingredients) manufacturing teams, including maintaining equipment, preparation of solutions, staging of equipment and supplies, and other various manufacturing support activities.

Job duties include :

  • Prepare buffer formulations for Drug Substance manufacturing, ensuring safety and quality, while maintaining cleanliness in the manufacturing area.
  • Perform routine processes, including buffer formulation, ultrafiltration, and chromatography. Maintain equipment, prepare reagents, and stock materials.
  • Clean production equipment and spaces used in the manufacturing process.
  • Execute daily tasks following cGMPs and quality-approved procedures, documenting all activities in compliance with GDP standards.
  • Dispose of cleaning and process waste safely, maintain supply stock levels using the Kanban system.
  • Ensure compliance with Safety and Quality guidelines by adhering to procedures, conducting safety inspections, performing preventive maintenance, and assisting with quality deviations.
  • Support departmental operations by training new employees, assisting with daily functions, and contributing to process improvement, safety, quality, and 6S initiatives in collaboration with the department supervisor.

Physical Attributes :

  • Stand for extended periods of time.
  • Lift, push, and or pull up to 50lbs.
  • Wear mask, safety shoes, gloves, Tyvek suits, respirator, and related personal protective equipment.
  • Who you are :

    Minimum Qualifications :

  • Associate Degree in Biology, Chemistry, or other life science discipline
  • 1 + years’ experience in a pharmaceutical GMP operations environment (Manufacturing, Quality, MSAT, Buffers).
  • Experience with Antibody Drug Conjugates (ADCs), including knowledge of their formulation and manufacturing processes
  • Preferred Qualifications :

  • Prior experience in an API manufacturing environment.
  • Strong mechanical aptitude.
  • Experience in Good Distribution Practices (GDP)
  • Demonstrated process improvement experience.
  • Familiarity with FDA, EMA, and other regulatory standards.
  • Demonstrated knowledge and experience in various computer skills, including Windows (Word, Excel, PowerPoint, etc.)
  • RSREMD

    Pay Range for this position :   $24.00 - $41.00.

    The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here .

    What we offer : We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

    Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

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