ScientistSpectraforce Technologies • South San Francisco, CA, United States
Scientist
Spectraforce Technologies • South San Francisco, CA, United States
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job_description.job_card.job_descriptionDegree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor. Prior industry experience in drug discovery / development is preferred. In-depth understanding of PK, TK and PK / PD studies and corresponding bioanalytical assays as well as in vitro characterization assays is highly desired. Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and / or Orbitrap (Thermo) mass spectrometers is highly desired. Hands-on experience with automated liquid handling systems is highly desired.
Position Title : Scientist
Work Location : South San Francisco, CA, 94080
Assignment Duration : 06 months
Position Summary : The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated scientist to join the Biologics bioanalysis, characterization, and proteomics group.
Background & Context :
The main function of this position is to develop and implement LC / MS (liquid chromatography / mass spectrometry)-based bioanalysis and in vitro characterization assays for novel biologics entities.
Key Responsibilities :
- Operate and maintain LC / MS instruments to generate high-quality experimental data.
- Perform affinity purification of therapeutic proteins (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices.
- Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
- Facilitate assay optimization and implementation to ensure laboratory capacity and data quality.
Communicate data interpretation internally and externally.
Qualification & Experience :
Hands-on experience with oligonucleotide analysis is highly desired.
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Scientist • South San Francisco, CA, United States
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