Scientist / Senior Scientist, Upstream

Job Description

Job Description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a highly skilled and motivated Upstream Scientist / Senior Scientist to join our team onsite in Redmond, WA. This individual will lead and execute upstream project process development (USP) and technology transfer activities to support the development of clinical manufacturing processes for our protein therapeutics pipeline. The ideal candidate will have hands-on experience with mammalian cell culture, bioreactor operations, and process scale-up for biologics production.

Responsibilities :

• Apply technical knowledge andin upstream process development for CHO cells (bioreactor process design, scale up, media and feed optimization, etc.), draft study protocol, design and execute experiments including in-process tests, characterize and deliver harvest material to downstream team,and author technical reports.
• Stay abreast of technical advancements in the CMC area of CHO cell line development and upstream process development and technology transfer aligned with cGMP clinical manufacturing.
• Support the transfer, development, and scale-up of CHO cell culture process technology from research into process development and manufacturing, to enable the production of clinical material
• Collaborate with teams in downstream process development and analytical development to advance recombinant protein programs
• Lead and support various elements of early-stage CMC development activities, including technical support of non-GMP and clinical manufacturing, as well as development and implementation of process improvements, as programs advance through development
• Analyze, interpret, present and document complex technical information in statistically meaningful ways. Exhibit and improvein DoE and multi variant analysis.
• Work with the team within the project scope, manage timeline in a fast-paced dynamic environment with rigor and agility.
• Data analysis, interpretation, and effective communication to management.

Qualifications :

This job description is intended to present the general content and requirements for this job. The description is not to be construed as an exhaustive statement of duties, responsibilities, or requirements. Managers and supervisors may assign other duties as needed.

Compensation and Benefits :

The expected base salary range for this position is $90,000 to $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.

While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise align strongly with the requirements of the role.

SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including : 100% paid employee premiums for medical / dental / vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

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