Senior Director, Development Information Systems

Overview

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

We are seeking an experienced life sciences technology professional to lead the planning, implementation, and ongoing support of technology solutions enabling success across Clinical Development, Regulatory Affairs, Medical Safety, Quality, and Pharmaceutical Development & Manufacturing. This critical leadership position, reporting to the VP of R&D Information Operations, will serve as the primary liaison between these business units and Information Sciences (IS), ensuring scalable, compliant, and business-aligned systems are in place as we advance toward commercialization. In this role you will :

• Build and maintain strong relationships with functional leaders in Clinical Development, Regulatory Affairs, Medical Safety, Quality, and Pharmaceutical Development & Manufacturing to understand their strategic goals and translate them into robust technology roadmaps.
• Lead and manage the technology portfolio of systems supporting regulated processes, ensuring scalability, compliance, and operational efficiency in preparation for commercial launch.
• Serve as the subject matter expert (SME) and IT thought partner for digital transformation initiatives within regulated domains.
• Oversee planning, budgeting, execution, delivery, and maintenance of key systems initiatives (e.g., CTMS, RIMS, PV Safety DB, QMS).
• Ensure systems are implemented in alignment with GxP and regulatory standards, including 21 CFR Part 11, GAMP5, and data integrity principles.
• Drive system governance, lifecycle management, and change control processes across all supported functions.
• Manage vendor relationships and SaaS contracts to optimize performance and compliance.
• Build, lead, and mentor a high-performing team of IT professionals and service providers.
• Ensure all supported systems meet regulatory, cybersecurity, and data privacy requirements.
• Partner with Quality, Validation, and Compliance to maintain inspection readiness across all technology-enabled processes.

Required Skills, Experience and Education

Preferred Skills

Compensation and Benefits

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Salary Range

$236,000 — $295,000 USD

Details

Location

Onsite at headquarters in Redwood City, CA.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity / expression, national origin / ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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