Clinical Research Site Lead
Reports To : Executive Director, Head of Site Operations
Department : Site Operations
Employment Type : Full-Time Onsite 40 hours Mon-Fri (must be flexible as lead)
Position Summary
The Clinical Research Site Lead is a hands-on leadership role responsible for the daily operations of a clinical research site. This individual serves as both a study coordinator and a line manager, ensuring high-quality study conduct, efficient participant logistics, and operational excellence. The Site Lead is the face of the site—representing it in cross-functional communications, driving team performance, and continuously identifying ways to improve processes and outcomes. This role offers a strong opportunity for growth into broader leadership within the clinical site network.
Key Responsibilities
People Management & Site Leadership
- Directly manage site-based staff, including Clinical Research Coordinators and support personnel.
- Track and report staff attendance, punctuality, and performance.
- Conduct regular coaching, performance reviews, and team development.
- Foster a culture of accountability, collaboration, and continuous improvement.
Participant Logistics & Experience
Oversee participant scheduling, visit flow, and onsite experience to ensure smooth, timely, and high-quality visits.Troubleshoot logistical challenges and implement solutions to improve participant satisfaction and retention.Ensure the site is always visit-ready and aligned with enrollment and retention goals.Study Conduct & Quality Oversight
Lead the execution of Phase II–IV investigational product studies as a hands-on coordinator.Ensure protocol adherence, data integrity, and regulatory compliance.Maintain audit readiness and support inspections as needed.Technology & Systems Proficiency
Ensure functionality and maintenance of all IT equipment (computers, tablets, printers, etc.).Oversee and train staff on the use of clinical systems including :AI-enabled toolsElectronic consent platformsElectronic source and regulatory filing systemsCTMS platforms (e.g., CRIO, Hubspot)Serve as the liaison with IT support for troubleshooting and upgrades.Operational Excellence & Site Representation
Act as the primary point of contact for the site, representing it in internal and external communications.Monitor and report on site productivity, efficiency, and performance metrics.Identify and implement process improvements to enhance operational efficiency and participant experience.Qualifications
Bachelor’s degree in a health-related field or equivalent experience.Minimum of 5 years of experience in clinical research, specifically as a Study Coordinator for Phase II–IV investigational product studies.At least 1–2 years of management or supervisory experience in a clinical or healthcare setting.Strong leadership, organizational, and communication skills.Proficiency in clinical trial software and Microsoft Office Suite.Demonstrated ability to manage participant logistics and lead site operations.Ability to travel between sites as needed.Preferred Skills
Experience with CRIO, Hubspot, or similar CTMS platforms.Familiarity with AI tools, eConsent, and electronic regulatory systems.Proven ability to lead teams, manage logistics, and drive operational excellence.We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable federal, state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance (FCIHO), Los Angeles Fair Chance Ordinance for Employers (ULAC), The San Francisco Fair Chance Ordinance (FCO), and the California Fair Chance Act (CFCA).
This position is subject to a background check based on its job duties, which may include patient care, working with vulnerable populations, access to financial and confidential information, driving, working with heavy machinery, or working in a warehouse or laboratory environment. Due to these job duties, this position has a significant impact on the business operations and reputation, as well as the safety and well-being of individuals who may be cared for as part of the job position or who may interact with staff or clients.