Scientist, Cell BiologyALS TDI • Watertown, MA, USA

Scientist, Cell Biology

ALS TDI • Watertown, MA, USA

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About Us : The ALS Therapy Development Institute (ALS TDI) is a leading non-profit biotechnology company dedicated to discovering and advancing effective treatments for amyotrophic lateral sclerosis (ALS). At ALS TDI, we are driven by our mission to find therapies that can make a real difference for patients living with ALS.

Position Overview : We are seeking a dynamic and highly motivated Scientist to join our Cell Biology research team. In this role, you will contribute to the development of advanced cell-based models of ALS and play a key role in chemical and genetic screening initiatives for drug target identification and therapeutic discovery. This is an exciting opportunity to work in a collaborative, mission-driven environment and make a tangible impact on ALS research.

Key Responsibilities :

Develop innovative induced pluripotent stem cell (iPSC)-based models of ALS using patient-derived fibroblasts and genome-edited cell lines.
Perform neural differentiations to generate cellular models for phenotype discovery.
Design, execute, and manage experiments with a high level of scientific rigor.
Analyze experimental data and present findings to the Cell Biology team and at company-wide meetings.
Stay informed of the latest scientific advancements and proactively share new ideas, methodologies, and insights with colleagues.

Minimum Qualifications :

Education : MS / MA or Ph.D. in Molecular and Cell Biology or a related field.

Experience : Proven experience with mammalian cell culture and general molecular and cellular biology techniques.

Preferred Skills : Background in neurobiology, stem cell biology, cellular immunology, genome editing, cell-based assay development, laboratory automation, or high-content cell analysis.

Attributes : Strong organizational and communication skills, attention to detail, and the ability to work both independently and collaboratively on multiple projects.

Why Join Us?

Be part of a passionate and innovative team dedicated to making a difference in the lives of ALS patients.

Collaborate in a cutting-edge research environment with opportunities for professional growth and development.

Contribute to impactful scientific discoveries that bring us closer to effective ALS treatments.

What We Offer

We offer a comprehensive benefits package designed to support your well-being and growth. Enjoy unlimited PTO, a generous holiday schedule, and a casual, collaborative work environment. Benefits include medical, dental, and vision coverage, HRA for out-of-pocket expenses, Health and Dependent Care FSAs, company-paid Life, AD&D, and Short- and Long-Term Disability insurance, and a retirement plan with company match. Additional perks include tuition reimbursement, MBTA pass, and gym access.

ALS-TDI is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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Scientist • Watertown, MA, USA