Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments. Stanford University is one of the world’s most renowned universities. Sitting in the heart of the San Francisco Bay Area among the valley’s most progressive companies. You will be working with an unparalleled leading-edge community of faculty and staff that are fundamentally changing the world of health care. You will have the opportunity to influence and drive change with your innovative ideas, the ability to make a difference and participate in human advancements. Our culture is fast-paced, energetic, and growing all of the time. We offer a variety of benefits beyond traditional medical, dental, retirement, and savings options : Events and program for children, sports camps, tuition options World-class intellectual stimulation through learning and development classes, workshops, and onsite conferences from leading-edge speakers and faculty Work / life and family-friendly policies and reimbursement Participation in Stanford’s social responsibility and sustainable programs for a better world A vibrant university culture that values the uniqueness of each individual We are seeking candidates who are progressive thinkers, see challenges as simply problems to solve, and have the spirit and energy to change the world. About the Department of Pathology The Department of Pathology is a founding department of the Stanford School of Medicine and one of the leading departments in the United States. Our preeminent faculty spans from emerging leaders to highly accomplished physicians and scientists, including a Nobel laureate and members of the National Academy. Our mission is to improve the diagnosis, treatment, and basic understanding of the human disease. This is done through discovery (research), education, and clinical care. Comprised of extraordinary faculty and staff, our mission is to improve the diagnosis, treatment and basic understanding of human disease. We accomplish this through our clinical services, research, and training the future leaders in pathology and related fields. A major focus of clinical research in the Department continues to be the correlation of patient outcome and treatment response. Everything we do is to provide the highest quality of pathology diagnostic services to the patients for whom we passionately care. For more information about the department visit http : / / pathology.stanford.edu / About the Position An LSRP position is available in the combined Lab of Dr. Brooke Howitt, Dr. Gregory Bean, and Dr. Gregory Charville, in the Department of Pathology at Stanford University. This opportunity allows for exposure to and involvement in a number of different research projects. Our lab studies various cancers including gynecologic, breast, gastrointestinal, and soft tissue sarcomas. We seek to understand the molecular underpinnings of human cancers, with the goal of developing new diagnostic, prognostic, and / or predictive biomarkers that can be applied in anatomic pathology clinical practice. Specifically, Dr. Bean’s research interests include the genomes and transcriptomes of special subtypes of breast tumors, including neuroendocrine carcinomas, salivary-like carcinomas, papillary carcinomas, and sarcomas, as well as precursor lesions in breast carcinogenesis. Dr. Charville’s research projects involve studying genetic and epigenetic features of various soft tissue sarcomas, including rhabdomyosarcoma and Ewing sarcoma. Dr. Howitt studies genetic, epigenetic, and transcriptomic characteristics of fallopian tube lesions, ovarian cancer, gynecologic sarcomas, endometrial carcinomas, and vulvar lesions. The LSRP will be involved in multiple defined research projects and will be responsible for independently conducting experiments and analyzing data with guidance from the PIs. Specifically, they will be doing molecular profiling (DNA sequencing, RNA sequencing, and methylome profiling) and biomarker analysis on a variety of human cancers. The position also includes lab management tasks such as ordering supplies, maintaining our slide / block / tissue inventory, keeping detailed lab records, and adhering to safety regulations. We welcome candidates with a growth mindset, interest in a variety of cancer research questions related to molecular underpinnings of disease, and a willingness to take on challenging learning opportunities. In addition to comparable research compensation, candidates will have the opportunity to learn and to develop their CV or resume through research publications and presentations. Duties include : Plan and perform experiments in support of research projects in lab and / or field based on knowledge of scientific theory. Interpret and perform basic analyses of results. DNA and RNA extraction from fresh, frozen, and / or formalin fixed paraffin embedded tissue, with subsequent library preparation and massively parallel sequencing (performed at a core facility). Sequencing data generated can be analyzed using existing software programs. Downstream experiments may include designing a targeted sequencing test, in situ hybridization, and / or immunohistochemical biomarker testing. Review literature on an ongoing basis to remain current with new procedures and related research. Offer suggestions regarding modifications to procedures and protocols in collaboration with graduate post-doctoral individuals. Maintain detailed records of experiments and outcomes. Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals. Help with general lab maintenance as needed; maintain lab stocks, manage chemical inventory and safety records, and provide general lab support as needed. Help orient and train new contingent staff and students Other duties may also be assigned Desired Qualifications : A bachelor’s degree in biological sciences or a related field. Previous experience (preferred) or established knowledge of basic laboratory techniques in molecular biology. Strong analytical skills and excellent judgment. Ability to work under deadlines with general guidance is essential. Must be accurate, efficient, organized and have excellent record keeping abilities. Ability to work with team members in a cooperative fashion. Excellent communication skills. Education & Experiences (Required) : Bachelor's degree in related scientific field. Knowledge, Skills and Abilities (Required) : General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed. Demonstrated ability to apply theoretical knowledge of science principals to problem solve work. Ability to maintain detailed records of experiments and outcomes. General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications. Ability to work under deadlines with general guidance. Excellent organizational skills and demonstrated ability to accurately complete detailed work. Physical Requirements
Research Professional • Stanford, CA, US