Vice President, Medical Affairs

Vice President, Medical Affairs

Using living cells to treat and sometimes even cure cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies have been successfully treated with cell therapies. However, these profound results have not yet been achieved in patients with solid tumors, representing approximately 90% of all cancers. And for patients with hematologic malignancies, there is a need for next-generation cell therapies that can deliver increased response rates and longer duration of response. We are a clinical-stage company advancing a pipeline of next-generation CAR T-cell therapies for patients with solid tumors or hematologic malignancies. Lyell's product candidates are enhanced with novel technology designed to generate T cells that resist exhaustion and have qualities of durable stemness in order to drive durable tumor cytotoxicity and achieve consistent and long-lasting clinical response. We were founded by cell therapy pioneers whose decades of research elevated the broader understanding of T-cell biology and its interaction with cancer. In our quest to advance next-generation CAR T-cell therapies, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Our culture is based on Science, Respect, Collaboration, and Courage and reflects who we are, the environment we create, and our mission's urgency. This role is a hybrid role and is based out of our South San Francisco, California office.

Position Summary

In this role, the Vice President, Medical Affairs will serve as a senior leader within Medical Affairs, reporting directly to the SVP, Medical Affairs. This role is responsible for leading U.S. Medical Affairs strategy and execution, ensuring scientific and medical excellence, and establishing Lyell as a trusted partner with external stakeholders. The Vice President will play a critical role in preparing for Lyell's first approval and commercial launch and in building and scaling a high-performing Medical Affairs team to support the current and future pipeline.

Key Role and Responsibilities

Strategic Leadership

• Lead the development and execution of U.S. Medical Affairs strategy in alignment with corporate and clinical objectives.
• Partner closely with the SVP, Medical Affairs to shape and evolve the overall vision for Medical Affairs.
• Provide senior medical leadership and insight across Clinical Development, Regulatory, Commercial, and Market Access functions.

External Engagement

Medical Excellence

Team Building

Compliance & Governance

Preferred Education & Experience

Knowledge, Skills and Abilities