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Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE), Across Therapeutic Areas

Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE), Across Therapeutic Areas

J&J Family of CompaniesSpring House, PA, US
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Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE)

Johnson & Johnson Innovative Medicine is recruiting for Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE), across therapeutic areas.

The primary location for this position is flexible Titusville, NJ; Raritan, NJ; Spring House, PA; Cambridge, MA; or San Diego, CA.

J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, immunology, neuroscience, cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market from patients to practitioners and from clinics to hospitals.

The R&D Data Science & Digital Health, Real-World Evidence (RWE) team at J&J Innovative Medicine is dedicated to developing innovative evidence solutions and critical insights through diverse data sources, including RWD, trial data and emerging innovative data sources, to support clinical programs and regulatory decision-making.

We are seeking a visionary Senior Director to lead Real-World Evidence (RWE) strategy and execution across therapeutic areas (xTA). This role will be pivotal in shaping the future of RWE at the organization - driving internal / external collaboration, advancing regulatory-grade evidence generation, and elevating our scientific leadership both internally and externally.

The successful candidate will partner closely with senior leaders across R&D and commercial to build an integrated, agile, and forward-thinking RWE ecosystem. This includes leading strategic initiatives, influencing regulatory policy, and representing organization as a thought leader in the global RWE community.

Key Responsibilities

  • Define and execute the RWE initiatives across therapeutic areas, ensuring alignment with long-term organizational goals.
  • Lead cross-functional RWE committees and foster high-impact partnerships with internal and external stakeholders.
  • Shape and elevate the enterprise-wide RWE ecosystem through innovation, governance, and capability building.
  • Serve as a strategic advisor on regulatory-grade evidence generation and policy shaping.
  • Lead preparation and presentation of scientific data packages for regulatory submissions and agency interactions.
  • Represent J&J in external forums to influence RWE standards and regulatory expectations.
  • Chair the Methodology Review Board (MRB) and oversee a portfolio of high-impact RWE projects.
  • Establish best practices for novel study designs and implementation.
  • Promote continuous learning and innovation in emerging RWE methodologies and technologies.
  • Develop frameworks and tools to scale evidence generation and accelerate delivery.
  • Champion a culture of scientific rigor, collaboration, and execution excellence.

Required qualifications :

  • Ph.D. or Master's in epidemiology, biostatistics, outcomes research, health policy, or related field.
  • 10+ years of relevant experience in biopharma, RWE consulting, or healthcare industries.
  • 7+ years of experience as a people manager.
  • Proven expertise in data extraction, cleaning, and analysis; strong grasp of advanced statistical methods.
  • Experience with diverse data sources (EHR, claims, registries, trial data, digital health).
  • Strong communication skills, with the ability to effectively engage both technical and non-technical stakeholders.
  • Proven leadership and influencing capabilities, with a track record of inspiring teams and driving cross-functional alignment.
  • Highly motivated and intellectually curious, with strong executional rigor and a passion for solving complex challenges.
  • Proficiency in R, Python, or SQL.
  • Preferred qualifications :

  • Expertise in regulatory-grade evidence generation and regulatory engagement.
  • Strong leadership in cross-functional initiatives and ability to influence without authority.
  • Subject matter expertise in key therapeutic areas including Oncology, Immunology, Neuroscience.
  • Experience in matrixed organizations and global stakeholder engagement.
  • Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

    Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

    The anticipated base pay range for this position is $173,000 to $299,000.

    Additional Description for Pay Transparency Employees and / or eligible dependents may be eligible to participate in the following : Company sponsored employee benefit programs : medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Employees are eligible for the following time off benefits : Vacation up to 120 hours per calendar year Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington up to 56 hours per calendar year Holiday pay, including Floating Holidays up to 13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year

    #JRDDS #JNJDataScience #JNJIMRND-DS

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