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Principal Automation Engineer
Principal Automation EngineerZipRecruiter • Laguna Beach, CA, United States
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Principal Automation Engineer

Principal Automation Engineer

ZipRecruiter • Laguna Beach, CA, United States
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Job Description

Ready to shape the next of clinical automation? Join a mission-driven team where your innovations directly impact patient care and scientific breakthroughs. This is more than a job—it’s a chance to engineer solutions that save lives.

Salary : $130,000 - $200,000 per year

A bit about us

Are you ready to take your automation expertise to the next level? We’re seeking a Principal Automation Engineer to lead groundbreaking innovation in clinical laboratory automation. This is your chance to design and implement cutting-edge solutions that directly accelerate advancements in patient care.

At our company, you won’t just be another engineer, you’ll be part of a mission-driven team that is transforming the way life, changing diagnostics are delivered. Here, your work doesn’t just improve processes, it improves lives.

Why join us?

  • Purpose-Driven Work : Every project you touch will help improve patient outcomes and advance the fight against cancer and other critical diseases.
  • Career Growth : We invest in our people with career coaching, leadership development, and extensive training opportunities.
  • Comprehensive Benefits : Competitive health plans (HMO & PPO), 401(k) with company match, Employee Stock Purchase Program, tuition reimbursement, generous PTO (16+ days plus holidays), and wellness resources.
  • Collaborative Culture : Join a team that values innovation, teamwork, and continuous learning in a fast-paced, world-class environment.

Job Details

As the Principal Automation Engineer, you’ll be at the forefront of designing, building, and optimizing automation for high-throughput clinical workflows. You will :

  • Engineer Next-Gen Workflows : Develop and implement automated solutions on advanced liquid handlers to support DNA / RNA extraction, Next-Gen Sequencing (NGS) library prep, and other molecular processes.
  • Innovate Across Teams : Partner with R&D, operations, and IT to create high-accuracy, scalable workflows that improve throughput and reliability.
  • Drive Integration : Connect automation platforms with Laboratory Information Management Systems (LIMS), ensuring seamless and secure data flow across multiple labs.
  • Advance Clinical Excellence : Contribute to assay development, validation plans, SOPs, and quality documentation to meet CAP / CLIA requirements.
  • Continuously Improve : Lead iterative design, testing, and refinement of automation workflows to enhance efficiency and reduce variability.
  • Be the Expert : Troubleshoot, optimize, and ensure long-term reliability of automated systems while mentoring peers and supporting multi-site deployments.
  • What You Bring

  • Bachelor’s degree in biology, engineering, biotechnology, or related field
  • 7+ years of experience developing automated molecular workflows on Hamilton or similar liquid handlers
  • Hands-on experience in CAP / CLIA-regulated laboratories
  • Strong background in molecular biology techniques, laboratory-developed tests (LDTs), or in vitro diagnostics (IVDs)
  • Proven success collaborating across R&D, clinical, and operations teams to deliver innovative solutions
  • Data-driven mindset, excellent problem-solving skills, and ability to thrive in a dynamic environment
  • Interested in hearing more? Easy Apply now by clicking the "Apply Now" button.

    Jobot is an Equal Opportunity Employer. We provide an inclusive work environment that celebrates and all qualified candidates receive consideration for employment without regard to status, genetics, protected veteran status, or any other characteristic protected by federal, state or local laws.

    Sometimes Jobot is required to perform background checks with your authorization. Jobot will consider qualified candidates with criminal histories in a manner consistent with any applicable federal, state, or local law regarding criminal backgrounds, including but not limited to the Los Angeles Fair Chance Initiative for Hiring and the San Francisco Fair Chance Ordinance.

    Company Description : Jobot is on a mission to connect good people with good jobs. By combining AI-powered technology with the expertise of Jobot Pros, our experienced recruiters, we help you find career opportunities that align with your goals and values. Founded in 2018 and employee-owned since 2024, Jobot is committed to fostering a culture of kindness, respect, innovation, and connection. Ready to find a good job? Create your profile today at Jobot.com.

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    Automation Engineer • Laguna Beach, CA, United States

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