Principal Mechanical Design Engineer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Roche Sequencing Solutions is expanding with a Principal Mechanical Design Engineer to lead the mechanical design, development, characterization, and integration of cutting-edge sequencing systems and advanced automation equipment. These systems encompass various subsystems such as fluidic, mechatronic, pneumatic, thermal, optical, and electrical components.

The Principal Mechanical Design Engineer will play a vital role in driving innovation for a highly automated DNA sequencing pipeline and other diagnostic applications. We are looking for someone that exhibits a high degree of motivation, independence, and resourcefulness to help us develop solutions to novel DNA Sequencing and automation challenges in a fast-paced and collaborative environment.

The Opportunity

• You will be responsible for the mechanical design of custom fluidic components, assemblies, and subsystems
• You will oversee the prototyping and testing of mechanical and electromechanical designs
• You will define and refine requirements and specifications
• You will be responsible for selecting and evaluating off-the-shelf components
• You will help with other critical functions including subsystem and system level assembly, testing and troubleshooting, as well as analyzing data, writing reports and presenting results.
• You will work closely with other engineers and scientists on integration efforts and provide guidance / oversight to other team members, consultants, contractors, and vendors.

Who You Are : (Required)

Preferred :

This is an on-site position based in Santa Clara, CA.

Relocation benefits are not being offered for this role.

The expected salary range for this position based on the primary location of Santa Clara, CA is $110,500 - $205,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.

Benefits

#RSS2025

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .