Senior Director, Real World Evidence (RWE) / Health Economics and Outcomes Research (HEOR)Waltham, Massachusetts

Senior Director, Real World Evidence (RWE) / Health Economics And Outcomes Research (HEOR)

At Kailera, we are bold, authentic and committed to our mission of developing therapies that give people the power to transform their lives and elevate their overall health. Rooted in an entrepreneurial spirit and a team-oriented culture, we are working together to advance Kailera's mission to advance novel therapies for obesity and related conditions. We are passionate about creating an inclusive workplace that promotes collaboration, integrity, and excellence. As we expand, we seek the most talented individuals with diverse backgrounds, cultures, perspectives, and experiences to join our team.

What You'll Do :

The Senior Director, Real World Evidence (RWE) / Health Economic Outcomes Research (HEOR) at Kailera Therapeutics will report to the VP of Medical Affairs. The Senior Director will lead the development and execution of our real-world evidence and health economics strategy to support novel therapies for obesity and related diseases. This role will play a critical role in shaping how our therapies are perceived by payers, providers, and the broader healthcare ecosystem. The Senior Director will collaborate cross-functionally to develop and implement RWE / HEOR strategies that demonstrate the value of our innovations in obesity care and related diseasessupporting access, adoption, and long-term impact.

Responsibilities :

• Lead the design and implementation of integrated RWE and HEOR plans to support Kailera's therapeutic programs from early-stage research through late-stage clinical development.
• Identify evidence gaps and prioritize real-world studies to inform treatment patterns, disease burden, patient-reported outcomes, and unmet needs.
• Support the development of value-based narratives to articulate the clinical, economic, and societal impact of our therapies.
• Responsible for building, managing, and inspiring a team to support innovative real-world evidence generation and health economics research.
• Design and oversee execution of real-world studies (e.g., burden of illness, cost-effectiveness, treatment adherence, comparative effectiveness).
• Develop and maintain global value dossiers, AMCP dossiers, and other evidence materials to support payer and HTA engagements.
• Publish and present findings at scientific congresses, peer-reviewed journals, and medical meetings to build the evidence base in obesity care.
• Partner with clinical development, regulatory, and commercial teams to align on RWE / HEOR strategy and execution.
• Serve as a scientific and strategic expert internally and externally, including with key opinion leaders, health economists, academic collaborators, and payers.
• Lead vendor selection and manage external research partners to ensure high-quality and timely study delivery.
• Ensure the development of needed resources to support engagement with population-based decision makers.
• Establish internal processes and best practices for RWE and HEOR in a fast-moving environment.
• Ensure compliance with all applicable ethical, regulatory, and privacy standards (e.g., GVP, GCP, GDPR, HIPAA).
• Contribute to overall medical affairs planning, launch readiness, and evidence strategy for upcoming milestones.

Required Qualifications :

Preferred Qualifications :

Education :

Benefits of Working at Kailera :

In addition to traditional benefits, we provide enhanced offerings designed to support the well-being and financial security of our team members and their families.

Salary Range $210,000 - $270,000 USD

Equal Employment Opportunity Information : Kailera Therapeutics, Inc. is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race (including traits historically associated with race, such as hair texture and protective hairstyles), color, creed, religion (including religious dress and grooming practices), national origin, ancestry, citizenship status, age (40 and over), sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, reproductive health decisions, domestic victim status, political affiliation, or any other characteristic protected by applicable federal, state, or local laws and ordinances.

E-Verify : Kailera Therapeutics, Inc. uses E-Verify to confirm the identity and employment eligibility of all new hires.