Histologist (Organ Perfusion)

Job Description

Job Description

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation : preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

About the Role

We are seeking an experienced, highly skilled Histologist—at the level of a senior research associate, scientist, or PhD-trained researcher—to lead histology assay development for evaluating mechanical and toxic damage in tissues following cryopreservation.

In this role, you will (1) design and implement histology assays from the ground up, selecting appropriate methodologies based on scientific needs, (2) collaborate with pathologists to generate high-quality, interpretable tissue health reports. (3) integrate additional molecular biology techniques such as western blotting and qPCR into the tissue processing pipeline, and (4) oversee tissue tracking, management, and processing, ensuring rigorous experimental data integrity from sample intake through imaging and quantification.

You will have the freedom to innovate, propose new approaches, and work across disciplines to improve our understanding of tissue health in the context of cryopreservation.

Key Responsibilities

• Lead the development and optimization of histology-based assays for tissue damage assessment.
• Collaborate cross-functionally with pathologists, molecular biologists, and engineers to design experiments that answer critical scientific questions.
• Manage end-to-end tissue sample workflows : labeling, tracking, processing, imaging, and archiving.
• Incorporate additional analytical methods (western blot, qPCR, immunohistochemistry) into the histology workflow.
• Ensure data quality and coordinate with the data science team for analysis and reporting.
• Survey literature and apply first-principles reasoning to identify and adopt novel histological and molecular techniques.

Qualifications

Benefits

While this represents our expected range based on market data, final compensation will be determined based on your specific qualifications and may be outside this range. Please keep in mind that the equity portion of the offer is not included in this estimate.

As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.