Associate Director, Global Translational Bioinformatics Lead

Astellas Pharma Inc.
Northbrook, IL
Full-time

Responsibilities :

  • Leads bioinformatics strategy and develop analysis plans to address asset team’s clinical development questions
  • Utilizes state of the art bioinformatics methods, internal and external data to address translational questions related to indication selection, patient segmentation, and biomarker identification
  • Conducts bioinformatics analysis of clinical trial omics data to support POM and patient selection
  • Supports data ingestion and conducts analysis using translational and biomarker data management platforms
  • Selects the appropriate data sets and analytical approaches for drug target identification and validation to support drug research
  • Develops new analysis tools and databases to meet the current and future portfolio needs
  • Identifies and evaluates external resources (CRO / academic collaborator) to complement internal capabilities

Requirements

Qualifications : Required

Required

  • PhD. in computational biology, bioinformatics, or other biomedical sciences with a minimum of seven years’ experience in applying bioinformatics approaches to drug discovery / development, preferably in a biopharma setting
  • Strong publication record in peer reviewed journals
  • Demonstrated experience in cancer genomics and omics data analyses, including experience with developing pipelines for next-generation sequencing data analysis and QC
  • Strong capability in designing and performing bioinformatics analyses to address translational questions, and to obtain insight on patient segmentation and biomarker selection
  • Excellent programming skills (including R, Python, SAS) and deep-knowledge for statistical analysis and machine learning
  • Experience with data visualization using web application such as Shiny / plotly
  • Experience with highly parallel, clustered, or supercomputing systems.
  • Complete independence in providing project level bioinformatics support, from planning to execution and reporting.
  • Strong communication skills and demonstrated ability to influence and lead in a matrix environment.

Preferred

  • Experience in analyzing single cell sequencing data and proteomics data
  • Experience in maintaining in-house Laboratory Informatics Management System (LIMS)
  • Administration experience of clustered-computing systems
  • Experience with human genetics data and RWD

Benefits :

  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Referral bonus program
  • 30+ days ago
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