In-vivo Experimentalist in Cancer Immunology - Higher Scientific Officer/Scientific Officer
In-vivo Experimentalist in Cancer Immunology - Higher Scientific Officer / Scientific Officer
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Key Information
Salary : Commencement on the salary range is subject to comparable skills and experience. Future progression is based on annual performance review.
This role is eligible for ICR Sponsorship at Higher Scientific Officer level. Support will be provided for costs associated with Visa application.
If you are considering relocating to the UK, further information can be found here. Due to UK visa requirements, we are unable to provide sponsorship at Scientific Officer level.
Duration of Contract : Fixed Term till February 2027
Hours per week : 35 hours per week (Full Time)
Closing Date : Sunday 1st September 2024, interviews will be held early / mid September.
Under the leadership of Professor Pascal Meier, we are seeking an enthusiastic Scientific Officer (SO) / Higher Scientific Officer (HSO) (depending on skills and experience) with experience in in-vivo assays to join the Meier laboratory.
The main responsibility of this position is to conduct in vivo experiments for the optimisation of novel therapeutic compounds aimed at driving a more potent anti-tumour immune response.
You will be using state-of-the-art syngeneic, immune competent murine tumour models to help with the development of novel PROTAC degraders of RIPK1 (Mannion et al., Immunity 2024).
Key Requirements
Applicants must have an appropriate degree and a current Home Office License, including modules A-C (modules 1-4). The ICR insists on high standards of animal welfare and meticulous record keeping in compliance with regulatory requirements.
You will have extensive hands-on experience working with genetically engineered murine models. We are seeking a team player able to confidently interact with members of different research groups.
Rigor in animal procedures, SOPs and protocols are key.
Experience using in vivo models is essential. Good organisational skills, and the ability to prioritise workload to meet project requirements will be essential.
Department / Directorate Information
The Cell Death and Immunity team led by Professor Pascal Meier uses a combination of sophisticated genetic models and patient-derived material to understand the complex relationship between Cell Death and Immunity, using this knowledge to destroy apoptosis-resistant cancers and re-activate the patient’s own immune system.
The Meier team identified that cell death mechanisms are tightly linked to immunity (Nat. Cell Biol. 2008, Mol. Cell 2011, Mol.
Cell 2017, Nat. Comms 2018, Mol. Cell 2018, EMBO Mol. Med. 2020, Nat. Comms 2021, Immunity 2024).
The successful candidate will work within a multidisciplinary team that involves the Centre for Cancer Drug Discovery, ICR, focussing on the development of novel compounds aimed at driving an anti-tumour immune response.
The Cell Death and Immunity team is part of The Breast Cancer Now Toby Robins Research Centre and the Centre for Translational Immunology at the ICR.
We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact [email protected].
About The Institute of Cancer Research
Why work for us?
As a member of staff, you'll have exclusive access to a range of staff benefits.
The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.
The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years.
Further information about working at the ICR can be found here.
We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world-leading cancer researchers of the future based on their application and performance at interview.
However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.
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