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Research Associate II - R&D USA - South San Francisco, CA

Research Associate II - R&D USA - South San Francisco, CA

Twist Bioscience CorporationSouth San Francisco, CA, US
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Research Associate II (Onsite in South San Francisco)

Job Description

The R&D team at Twist is searching for a curious, thoughtful, and driven individual with excellent lab hands to help us develop new products and applications in the Next-Generation Sequencing (NGS) space. Leveraging our silicon-based, massively-parallel DNA synthesis platform, you will conduct laboratory studies to develop, improve, and troubleshoot our latest NGS products. In this position, you will have the opportunity to work on leading-edge products for genomics, diagnostics, and personalized medicine.

First and foremost, we are looking for someone with a scientist's mindset. Creativity, critical thinking, careful experimental execution, and a desire to learn deep technical details are a must.

As Research Associate II, you will work on new product development and existing process improvement. Your work will be mainly at the bench, however, you will have the opportunity to use high-throughput robotic instruments as well as bioinformatics tools to expand your expertise. You will work alongside and learn from some of the best scientists and bioinformaticians in the business.

Key responsibilities :

  • Design and perform experiments in collaboration with scientists and bioinformaticians, under aggressive timelines
  • Evaluate, optimize and troubleshoot NGS-based workflows and assays to improve performance
  • Document experimental designs and results; keep excellent records and data
  • Analyze experimental data to provide recommendations for the next experimental steps
  • Present and communicate experimental results to multidisciplinary team members
  • Support the larger R&D team in various lab / day-to-day operations and activities across the board

Requirements :

  • S. with 2-3 years or M.S. with 1-2 years of experience in Molecular Biology, Biochemistry, Chemistry or a closely-related field
  • Must have strong background in molecular biology techniques and hands-on experience with methods for manipulating and analyzing nucleic acids (e.g. DNA / RNA extraction, purification and quantification, PCR, enzymatic assays, hybridization and primer design)
  • Hands-on experience with NGS and NGS applications (e.g. library preparation, target enrichment, sequencing and sequencing data analysis)
  • High attention to detail. Ability to identify problems and use a combination of knowledge, intuition, and experience to solve problems in a timely manner
  • Self-motivated and passionate about your work
  • Excellent interdisciplinary communication skills required
  • Willing and able to grow with a fast-paced, highly-collaborative, multidisciplinary team
  • Preferred Qualifications :

  • Industry experience, especially involving massively-parallel sequencing technologies and / or target enrichment
  • Fundamental background in dPCR, ddPCR or qPCR is preferred
  • Bioinformatics and programming skills (python, R, shell scripting)
  • Experience with liquid handling systems and automation tools
  • Familiarity and / or interest in either liquid biopsy and / or LIMS system a plus.
  • About Twist Bioscience

    Twist Bioscience synthesizes genes from scratch, known as "writing" DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

    At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

    Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

    The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

    $89,038 - $104,664 USD

    Voluntary Self-Identification

    For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

    As set forth in Twist Bioscience's Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

    If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows :

  • A "disabled veteran" is one of the following : a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
  • A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
  • An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
  • An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
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    Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

    Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov / ofccp .

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  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV / AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and / or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson's disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit / hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
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