Senior /Principal Scientist position – LynxBio (San Diego)

This opening is for a full-time, on-site position in sunny San Diego, CA, to be filled ASAP.

About the position :

Is your CV ready If so, and you are confident this is the role for you, make sure to apply asap.

We are looking for a highly motivated Senior / Principal Scientist (title commensurate with experience) with a strong background in fluorescence microscopy imaging and immuno-oncology / oncology.

This position is primarily laboratory-based and requires strong experimental experience with cell-based assays, fluorescence microscopy, and data analysis & visualization.

As an integral part of our R&D team, you will demonstrate world-class research skills and drive cross-disciplinary assay development projects.

Most importantly, you will play a key role in scaling up our multi-omics platform! You will operate with a high level of autonomy, but also demonstrate strong interpersonal skills and the ability to influence multidisciplinary teams.

Frequent interactions with internal and external stakeholders require a collaborative work ethic, strong communication & presentation skills, and the capacity to prioritize to meet critical goals.

In this role, you will :

• Drive R&D efforts to develop assays utilizing our proprietary multi-omics platform and incorporate new technologies to accelerate the discovery and development of innovative immune-oncology therapies.
• Execute technical and laboratory aspects of in-house assay development projects, including designing and executing major experiments and testing programs, evaluating test data, and preparing associated documentation and reports.
• Author study protocols, develop processes, prepare laboratory documents, such as SOPs, forms, and technical reports, in support of assay validation transfer.
• Prioritize and manage team resources to best achieve company objectives.
• Prepare & communicate highly technical methods and report team progress to a wider audience (internal and external).
• Support strategic collaboration projects and serve as project lead as appropriate.

Required Experience :

• MSc or PhD degree in a relevant scientific discipline
• 2-5+ years of experience with cell-based assays in drug discovery, cancer biology, or related fields
• Excellent understanding of HC / HT imaging and data analysis

Required Skills and Competencies :

• Strong background in cell & molecular biology and oncology / immuno-oncology
• Extensive experience in cell culture techniques, cell separation and expansion, IF assays, fluorescent microscopy, and image analysis / software (e.

g., MetaXpress, CellProfiler, ImageJ)

• Demonstrated experience in developing CBAs, ideally using primary patient samples
• Track record of good experimental design, independent, in-depth data analysis and interpretation based on strong scientific rationale
• Must be curious and enjoy working collaboratively in cross-functional teams
• Must be a self-starter and strong individual contributor who excels in open, collaborative environments
• Must be able to maintain detailed records in a regulated environment

Nice to have :

• Background in hematological malignancies
• Experience with multi-omic assays and analysis
• Biopharma collaboration / strategic partnering experience
• Familiarity with development and / or commercialization of cell-based assays / therapeutics
• Experience with Python, R, GraphPad Prism, Matlab
• Experience with microfluidic devices and miniaturized assays
• Experience working in / developing assays for a CLIA laboratory
• Experience with automation integration

Perks you will enjoy at LynxBio :

• Meaningful equity in a growing company and competitive compensation offerings, including outstanding healthcare benefits
• A dynamic and collaborative team environment.
• Flexible, generous vacation / sick leave policy
• State-of-the-art facility situated on the Torrey Pines Mesa, San Diego’s premier life sciences cluster, surrounded by numerous prestigious institutions, government agencies, and biotechnology companies.
• Headquarters with indoor vehicle parking, electric car charging, bike parking, and on-site showers & towel service
• On-site cafeteria with health-oriented, chef-prepared breakfast and lunch meals
• Company happy hours* and an always well-stocked snack bar
• Easy access to hiking trails, Torrey Pines State Reserve trailheads (1.3 mi), Torrey Pines golf course, and Torrey Pines State Beach (2.7 mi)
• Did we mention San Diego weather ?

More about us :

Lynx Biosciences, Inc. (LynxBio) is a clinical-stage precision oncology company combining physiologically relevant coculture assays, automated microfluidics, and integrative multi-omics with deep learning analytics to rapidly advance drug candidates in oncology and bring personalized cancer treatments to patients.

As a company at the intersection of biology and technology, we firmly believe in a data- and technology-driven approaches to decipher the complexity of cancer and create next-generation therapeutics.

We are being incubated by J&J Innovation and currently collaborate with Top-5 and Top-20 biopharma companies, academic institutions, and clinical key opinion leaders to develop next-generation therapeutics.

Our team members hail from all over the world, with a diverse set of backgrounds and areas of expertise. We are looking for passionate candidates who thrive in a fast-paced team environment, working collaboratively across multiple disciplines to contribute to the expansion of our technology platform.

At Lynx Biosciences, Inc. (LynxBio), we are proudly committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants and teammates.

We believe that diversity and inclusion among our teammates are critical to our success as a company, and we seek to recruit, develop, and retain the most talented people from a diverse candidate pool.

All aspects of employment will be based on merit, competence, performance, and business needs.

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