Associate Biomedical Scientist - Proteomics - Precision Biomarker Lab

Release the power of precise proteomics at Cedars-Sinai!

Join us as a scientist in cutting-edge quantitative proteomics to commercialize assay workflows and biomarkers for the diagnosis and treatment of human diseases and preventive health.

Precision Biomarkers Laboratories (PBL) at Cedar-Sinai, is seeking a candidate with comprehensive experience in the development of novel, high performance quantitative mass spectrometry workflows for proteins, including post-translation modifications (PTM’s).

You will have access to state-of-the-art LC-MS platforms (Thermo Exploris480, Thermo Astral, Sciex 6500+, Bruker tims-TOF) enabling quantitative proteomic profiling and development of assays using both high- and low- resolution techniques.

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Are you ready to be a part of breakthrough research?

This position requires an individual with outstanding technical skills and scientific experience as well as excellent communication and collaborative skills.

The individual must be able to work in a fast-paced clinical and product development environment to translate insights using proteomics into biomarker hypotheses that can be verified in large cohort studies.

You will be highly motivated, with a proven record of scientific productivity, excellence in communication, collaboration, and enthusiasm to join a growing, dynamic group.

Your motivation, innovation, and attention to detail will augment your ability to work collaboratively. This is a unique opportunity to join a dynamic ecosystem that leverages disruptive innovation from internal academic research labs and the clinical healthcare infrastructure.

Department-Specific Responsibilities :

• Direct experience developing state-of-the-art proteomic workflows, developing technology, and working independently.
• Experience across the entire proteomic workflow from sample prep to data analysis.
• In-depth understanding of various quantitation technologies including PRM and DIA, and their clinical applications.
• Strong theoretical understanding of protein biochemistry and practical knowledge of bottom-up proteomics.
• Hands-on experience with Thermo and Sciex mass spectrometry platforms.
• Familiarity with mass spectrometry analysis software (vendor-specific and open source).
• Extensive experience in instrumentation, troubleshooting, QC, standardization for proteomics workflow, and pipeline development.
• Demonstrated scientific productivity and excellent oral and written communication skills.
• Ability to manage multiple projects and timelines.
• Willingness to think outside of the box to drive the implementation of innovative proteomic workflows that align with the business unit objectives.

Education :

Bachelor's Degree in molecular biology, microbiology, biochemistry, or related science / engineering field required. Doctorate, preferred.

Experience and Skills :

• Five (5) years experience in mass spectrometry driven proteomics, especially in areas directly applying to human health.
• Experience with laboratory automation is desirable.
• Previous industry experience is advantageous.
• Demonstration of subject matter expertise through study designs and superior technical customer service is desirable.
• Coding skills (R, Python) for data analysis, and the ability to use / evaluate open-source software packages for processing mass spectrometry data are preferred.
30+ days ago