Scientist II/Senior Scientist - R&D

Job Description

Job Description

Eitr Biologics, Inc., (Eitr) is a San Diego, CA based biotechnology company focused on the pursuit of novel next generation immunotherapeutics for the treatment of infectious diseases that are a current or emerging threat to public health.

Our scientific approach emphasizes the development of technologies that will increase global accessibility to lifesaving immunotherapeutics.

Eitr has fostered a robust and highly collaborative worldwide network of academic and government laboratories that share in our scientific goal to address unmet public health needs.

Eitr scientists can expect to work in a collaborative atmosphere to advance promising early-stage exploratory technologies to clinical stages of drug development.

Eitr currently has an opening for a Scientist II / Senior Scientist Research and Development position, requiring the qualifications and responsibilities listed below.

Responsibilities

• Construct design, molecular cloning, multi-piece DNA assembly, site-directed mutagenesis and preparation of phage libraries
• Design and perform phage display based experiments (e.g., cloning, panning / screening, sequencing, etc.)
• Generate and characterize stable mammalian cell lines
• Characterize antibodies and antibody-based therapeutics (for e.g. affinity, specificity, cross-species binding, epitope determination)
• Records experimental data and writes data summaries in electronic formats
• Draft technical reports, as necessary
• Perform protein expression experiments
• Performs experiments including SDS-PAGE, UV / Vis Spectroscopy, ELISA, BLI and Western Blot
• Contributes to writing grant or contract proposals
• Other duties as assigned

Requirements

Basic Qualifications

• Ph.D. in a biology related discipline with 2+ years of post-graduate experience in an academic and / or industry setting
• Demonstrated mastery of standard molecular biology techniques (e.g., primer design, DNA / RNA preparations, PCR, cloning)
• Experience with antibody phage display including library construction, panning, screening by ELISA and FACS, and characterization
• Strong desire to formulate and execute experimental designs in an efficient manner
• Experience managing junior scientists
• Experience with mammalian cell tissue culture, transient transfection, and cell line development
• Knowledge of protein biochemistry
• Ability to follow written procedures / protocols precisely
• Ability work independently to complete given tasks and analyze resulting data
• Good communication, interpersonal, and teamwork skills are essential

Preferred Qualifications

• Experience with Biolayer Interferometry
• Experience independently designing and troubleshooting experiments
• Experience with infectious disease immunotherapeutics
• Experience with antibody formats including scFv, IgG, VHH, & multi-specifics
• Experience with bioinformatics software for sequence analysis such as PipeBio
• Experience with broad set of cell-based assays including reporter assays, FACS competition, ADCC, ADCP, CDC

Physical Demands of the Position Offered

The physical demands described here are representative, but not exhaustive, of those that must be met by an employee to successfully perform the essential functions of this laboratory position.

Reasonable accommodations may be made to enable individuals with disabilities to perform these essential functions.

On-site role : This is a full-time position that requires the employee to physically report to the jobsite.

Lifting and Carrying : This position may require the ability to lift and carry laboratory equipment, glassware, and supplies weighing up to 40 pounds on occasion.

Employees should be able to safely use appropriate equipment and follow proper lifting techniques.

Fine Motor Skills : Precise fine motor skills are essential for tasks such as pipetting and operating delicate laboratory equipment.

Candidates should demonstrate manual dexterity and hand-eye coordination.

Standing and Walking : Laboratory work often involves prolonged periods of standing and walking while conducting experiments, monitoring equipment, and moving between workstations.

Sitting : Data analysis, documentation, and report writing are integral aspects of this role, requiring the ability to sit at a desk or workstation for extended periods.

Bending, Stooping, and Reaching : Employees may be required to bend, stoop, and reach to access equipment, samples, or materials on upper or lower shelves or within laboratory hoods.

These activities may involve climbing ladders, stairs, step stools, or other structures. Candidates should be able to safely perform these tasks.

Vision : Good vision is essential for tasks such as reading labels, observing specimens, and using microscopes. Corrected vision and color vision may be required for accurate analysis.

Hearing : Laboratory environments may include equipment that produces noise. Adequate hearing is necessary for communication and safety awareness.

Use of Laboratory Equipment : Proficiency in the safe operation of laboratory equipment, including centrifuges, microscopes, and pipettes, is expected.

Laboratory Safety : Compliance with safety protocols, including the use of personal protective equipment (PPE) such as lab coats, gloves, safety goggles, and respiratory protection where required is mandatory.

Chemical Handling : The handling of chemicals and biological materials is a fundamental aspect of bioscience laboratories.

This may include the ability to safely handle and transport hazardous materials.

Working with Biological Agents : Some positions may involve working with biological agents, which may require adherence to specific safety protocols and vaccinations.

Team Collaboration : Effective communication and collaboration with team members are essential for data sharing, experimental planning, and project coordination.

Candidates should be aware that the physical demands listed above are general guidelines and may vary depending on the specific role and workplace.

It is important for applicants to inquire further about the physical requirements during the interview process to ensure they can perform the job safely and effectively.

Benefits

Eitr reasonably expect the annual base compensation for this role to be between $110,000 and $145,000. Subject to certain terms and conditions, the role will be eligible for a generous PTO policy including vacation, sick, and holiday time, 100% medical, dental, and vision coverage, and up to 6% 401(k) contributions.

Eitr is committed to a policy of Equal Employment Opportunity and will not discriminate against an applicant or employee based on race, color, religion, creed, national origin or ancestry, sex, age, physical or mental disability, veteran or military status, genetic information, sexual orientation, or any other legally recognized protected basis under federal, state, or local law.

The information collected by this application is solely to determine suitability for employment, verify identity, and maintain employment statistics on applicants.

Eitr is also committed to providing reasonable accommodations to individuals with disabilities. If you need a reasonable accommodation for any part of the employment process, please let us know the nature of your request and your contact information.

Eitr is not currently hiring foreign national applicants that require or will require sponsorship tied to a specific employer, such as H, L, TN, F, J, E, O.