Bio-conjugation / Translational Research Scientist
Pay : $66.50
Responsibilities :
This is a Bio-conjugation Scientist role with MRL SSF Discovery Chemistry group.
Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at our South San Francisco, CA site.
The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent Client medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
Specific responsibilities will include :
- Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
- Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
- Acquisition and interpretation of analytical data such as LC / MS.
Qualifications :
Minimum qualifications include a B.S. / M.S / PHD in chemistry, biochemistry, or related field, with industrial or academic experience.
Experience and Skills Required :
- Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques / instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.
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