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Principal Automation Engineer

Principal Automation Engineer

JobotLaguna Beach, CA, United States
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Overview

Ready to shape the next generation of clinical automation? Join a mission-driven team where your innovations directly impact patient care and scientific breakthroughs. This is more than a job—it’s a chance to engineer solutions that save lives.

Base pay range : $130,000.00 / yr - $200,000.00 / yr

Job details : This Jobot Job is hosted by Brendan Thomas. Easy Apply is available by clicking the "Easy Apply" button and sending us your resume.

Salary : $130,000 - $200,000 per year

Responsibilities

  • Engineer Next-Gen Workflows : Develop and implement automated solutions on advanced liquid handlers to support DNA / RNA extraction, Next-Gen Sequencing (NGS) library prep, and other molecular processes.
  • Innovate Across Teams : Partner with R&D, operations, and IT to create high-accuracy, scalable workflows that improve throughput and reliability.
  • Drive Integration : Connect automation platforms with Laboratory Information Management Systems (LIMS), ensuring seamless and secure data flow across multiple labs.
  • Advance Clinical Excellence : Contribute to assay development, validation plans, SOPs, and quality documentation to meet CAP / CLIA requirements.
  • Continuously Improve : Lead iterative design, testing, and refinement of automation workflows to enhance efficiency and reduce variability.
  • Be the Expert : Troubleshoot, optimize, and ensure long-term reliability of automated systems while mentoring peers and supporting multi-site deployments.

What You Bring (Qualifications)

  • Bachelor’s degree in biology, engineering, biotechnology, or related field
  • 7+ years of experience developing automated molecular workflows on Hamilton or similar liquid handlers
  • Hands-on experience in CAP / CLIA-regulated laboratories
  • Strong background in molecular biology techniques, laboratory-developed tests (LDTs), or in vitro diagnostics (IVDs)
  • Proven success collaborating across R&D, clinical, and operations teams to deliver innovative solutions
  • Data-driven mindset, excellent problem-solving skills, and ability to thrive in a dynamic environment
  • Why join us

  • Purpose-Driven Work : Every project you touch will help improve patient outcomes and advance the fight against cancer and other critical diseases.
  • Career Growth : We invest in our people with career coaching, leadership development, and extensive training opportunities.
  • Comprehensive Benefits : Competitive health plans (HMO & PPO), 401(k) with company match, Employee Stock Purchase Program, tuition reimbursement, generous PTO (16+ days plus holidays), and wellness resources.
  • Collaborative Culture : Join a team that values innovation, teamwork, and continuous learning in a fast-paced, world-class environment.
  • Equal Opportunity Employer : Jobot provides an inclusive work environment that celebrates diversity and considers all qualified candidates for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by law. Background checks may be performed where permitted.

    Interested in hearing more? Easy Apply now by clicking the "Easy Apply" button.

    Employment type

  • Full-time
  • Job function

  • Engineering and Information Technology
  • Industries

  • IT Services and IT Consulting and Software Development
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