Research Associate - Neural Plasticity

Job Description

Job Description

Description : A little about us :

The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.

We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.

Job Summary :

We are seeking an enthusiastic and self-motivated individual to join our group as a Research Associate. This position is best suited for candidates with significant experience in molecular biology, next generation sequencing, library prep, FACS sorting, and microscopy. The successful applicant will work within a dynamic team-based environment in a translational research setting with a focus on spatial transcriptomics projects in postmortem human brain tissue. Projects aim to generate transcriptome-scale maps in the human brain to understand differences in spatial gene expression in neuropsychiatric disorders. The Research Associate will thoughtfully conduct experiments, analyze data, participate in experimental design, and train junior personnel

Overview of Duties :

• Assist with brain tissue dissections
• Cryosectioning postmortem human brain tissue
• RNA extraction and qPCR
• RNA-seq library construction
• Nuclei isolation and FACs sorting
• Immunocytochemistry and single-molecule fluorescent in situ hybridization
• Confocal microscopy and slide scanning
• Data analysis in MATLAB and R programming languages
• This position description is intended to serve as a summary of the general purpose and essential functions of this position. It may change as circumstances warrant and may include other duties as deemed necessary by management.

Requirements :

Professional and Education Requirements :

Familiarity with any of the following is a plus :

o Neuroanatomy

o Confocal microscopy

o Programming in MATLAB, R or Python

Required Special Knowledge, Skills and Abilities :

Physical Requirements :

Compensation

Candidates are hired within the starting salary range for the position which is the lower portion of the overall range. The starting salary range for this position is $52k - $55k with opportunities for employee growth over time. Placement in the starting range is based on job-related skills and experience, as evaluated throughout the interview process.

Benefits

The Lieber Institute for Brain Development offers a competitive, comprehensive benefits package to help us attract and retain the best talent. Please visit https : / / www.libd.org / careers / benefits / for more information.

EEOC Statement : At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity / expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.

LIEBER INSTITUTE FOR BRAIN DEVELOPMENT'S COMMITMENT TO DIVERSITY, EQUITY, AND INCLUSION

The Lieber Institute for Brain Development is a transparent and collaborative community working to produce unique and imaginative patient-oriented solutions to developmental neuropsychiatric disorders. It is committed to integrating scientists from diverse disciplines, cultures, and countries into a research team that draws upon the best of its staff. The Institute is historic—it is defining a unique model for ground-breaking science. It values translational science that revolutionizes the field and improves the quality of life for those affected by mental illness. The Institute provides an environment that fosters independent growth through mentorship and a supportive, collegial community. Diverse minds, ideas, and talent are needed to support LIBD's mission. Fresh, innovative ideas and perspectives are a competitive necessity in an increasingly diverse and global marketplace. The success of the Institute's mission depends upon leveraging a diversity of talent.

The Institute's commitment to diversity goes beyond compliance with laws and regulations that promote equal employment opportunity, prohibit discrimination and harassment, and support minority and woman owned businesses. To realize the advantages of its diversity, it is necessary to work effectively together even when differences challenge us to consider ideas and methods that seem impractical or make us feel uncomfortable.

The Lieber Institute for Brain Development demonstrates its commitment to diversity by :