Senior Associate Scientist or Scientist, RNA Process Development

Immediate need for a talented Senior Associate Scientist or Scientist, RNA Process Development . This is a 12+ Months contract with possible extension opportunity with long-term potential and is located in Seattle, WA (Onsite).

Please review the job description below and contact me ASAP if you are interested.

Job ID : 24-38693

Pay Range : $60 - $68 / hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities :

• Design and execute nucleic acid ligation reactions using splint ligation methodology.
• Design and execute ion-pairing (IP) reversed-phase (RP) chromatography methods.
• Perform purification of oligonucleotides using chromatography and / or preparative PAGE.
• Design and evaluate the performance of new biophysical assays to identify and assess CQA’s.
• Manage samples and data related to gene editing platform process development.
• Provide experimental design and executional support to team members in adjacent and related functions (e.g. clinical development programs, high throughput process development, etc.).
• Actively participate and support lab maintenance and continuous improvement initiatives.
• Maintain accurate and detailed laboratory notebook and documentation.
• Summarize and present data in group meetings and contribute to group discussions.
• Author technical reports, study memos, and protocols.

Key Requirements and Technology Experience :

• Key Skills : Proficiency with biochemical techniques to analyze oligonucleotides (PAGE and CE).
• Proficiency with analytical IP-RP chromatography for RNA (including mRNA) purity.
• Experience working with, storing, and analyzing purified nucleic acids and proteins.
• Experience with optimizing molecular cloning reactions.
• Experience with gene editing primary human cells or immortalized cell-lines.
• STEM degree with 2+ years of relevant industry experience; title / compensation will be commensurate with education, experience, and skillset.
• Proficiency with biochemical techniques to analyze oligonucleotides (PAGE and CE).
• Proficiency with analytical IP-RP chromatography for RNA (including mRNA) purity.
• Experience working with, storing, and analyzing purified nucleic acids and proteins.
• Independently motivated with the ability to work in teams.
• Ability to communicate clearly and concisely through oral presentation and technical writing.
• Ability to leverage literature, internal and external resources to solve problems and develop new technologies.
• Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment.
• Degree in biological or chemical engineering, biochemistry, or bio-related field.
• Experience with optimizing molecular cloning reactions.
• Experience with gene editing primary human cells or immortalized cell-lines.
• Experience with solid-phase oligonucleotide synthesis.
• Experience with bioinformatic tools used to predict RNA secondary structure.
• Experience with JMP for DoE design and analysis.

Our client is a leading Pharmaceutical Industry, and we are currently interviewing to fill this and other similar contract positions.

If you are interested in this position, please apply online for immediate consideration.

Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.