Clinical Research Manager (GI / GU / Sarcoma)

Clinical Research Manager (GI / GU / Sarcoma)

The Clinical Research Manager is responsible for the implementation and conduct of clinical research trials in the Cancer Clinical Trials Office (CCTO) at the University of Colorado Cancer Center. This position is responsible for the oversight of all clinical studies and research staff in assigned programs.

Examples of Work Performed :

40% Clinical Trial Management and Administration :

• Oversees 1 to 3 different disease sites at a given time.
• Manages all staff updates in prescribed databases.
• Manages all Protocol Amendments for disease sites and disseminates changes to team (budget, regulatory, and UCH team members) and updates prescribed databases. Promotes quality study flow and ensures all governing regulations are being adhered to. Reviews Medicare Analysis reviews for each new Amendment for applicable disease sites.
• Acts as an interdepartmental liaison with UCH clinic staff (incl. investigators, nurses, clinic support staff, laboratory, pharmacy, radiology).
• Plans and directs investigator and coordinator meetings (i.e. Initial orientations, study audits, closeout visits, physician meetings, research team meetings.) or delegates responsibility to team members as appropriate.
• Works with budget and regulatory specialist on escalation plans with Contract Research Organizations and Sponsors as needed for resolution of outstanding issues (i.e. financial payment, budget updates, and closeout costs.)
• Oversees team schemas as studies are amended for eligibility, cohort changes, additional arms added, and study closeout.
• Participates in cost savings / productivity strategies to meet or improve the department's operational budget; reviews quarterly finance reports for designated clinical research programs and works with the finance team to resolve discrepancies and review account balances on a regular basis. Provides review and corrections to quarterly financial / clinical dashboards.
• Participates in preparation for, conduct of and generation of responses to external audits and FDA Inspections, and Data Safety Monitoring audits.
• Collaborates with Data Safety Monitoring Committee, Protocol Review Monitoring Committee, and Oncology Clinical Research Support Team on initiatives.
• Works with the Oncology Clinical Research Support Team staff on Investigator Initiated Trials reviewing protocol, amendment changes, and clinical toolkit.
• Assists investigators with miscellaneous tasks as applicable (i.e. team reports, community engagement, full team and PI meetings).

40% Personnel Development and Management :

20% Departmental Process Improvement, Guidance Development, and Collaboration :

Work Location :

Hybrid this role is eligible for a hybrid schedule of at least 3 days per week on campus and as needed for in-person meetings in Aurora, CO.

Why Join Us :

The University of Colorado Cancer Center stands at the forefront of cancer research and patient care in Colorado. As the state's only National Cancer Institute (NCI) designated Comprehensive Cancer Center, we hold a prestigious distinction that acknowledges our exceptional contributions to the fields of research, clinical trials, prevention, and cancer control. Our guiding vision is clear : "prevent and conquer cancer. Together." At the heart of our mission is the work to "unite our community to overcome cancer through innovation, discovery, prevention, early detection, multidisciplinary care, and education."

Our more than 300 members, made up of renowned physicians and researchers, conduct patient-centered research to develop innovative, state-of-the-art technologies, and treatments. Crucial to this work is the nearly 300 staff members who help expand the reach of the CU Cancer Center. Our expertise across cancer types helps us provide world-class treatment for common cancers, while offering hope for many patients with difficult or aggressive cancers who have struggled to find treatment options elsewhere.

Benefits statement to include in all benefits-eligible positions :

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including :

There are many additional perks & programs with the CU Advantage.

Qualifications :

Minimum Qualifications :

Preferred Qualifications :

Knowledge, Skills, and Abilities :

How to Apply :

For full consideration, please submit the following document(s) :

Questions should be directed to : cole.sprague@cuanschutz.edu

Screening of Applications Begins :

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by October 24, 2025. Those who do not apply by this date may or may not be considered. Hiring department will need to notify their Talent Acquisition Consultant when they want to have the advertisements removed for the posting.

Anticipated Pay Range :

The starting salary range (or hiring range) for this position has been established as HIRING RANGE (minimum 40th posting max). $71,244-$90,622. The above salary