Senior Director, Head of Protein and Bioanalytical Solutions

ROLE SUMMARY

Pfizer is seeking a Senior Director to lead the Protein and Bioanalytical Sciences (PBS) Research team. This multidisciplinary team is at the forefront of creating protein reagents, antibodies, and antibody-drug conjugates (ADCs) for both preclinical discovery research and exploratory toxicology studies.

The PBS team responsibilities includes the biophysical characterization of biologics, drug formulation, stability testing of new therapeutic compositions, and the bioanalytical assessment of ADC payload release and cellular deposition.

The appointed leader will drive a dynamic and collaborative team, focusing on expanding technological capabilities to enhance the capacity and efficiency of key material delivery, crucial for advancing the discovery of novel ADCs aimed at cancer treatment.

As a strategic and operational cornerstone, the PBS team leader will collaborate with other senior members of the ADC Discovery Research Group to build and drive Pfizer's ADC strategy and advance Pfizer's preclinical pipeline.

KEY RESPONSIBILITIES

• Lead a team of 30+ scientists including PhD level
• Accountable for appropriate resourcing and timely delivery of requested materials and data to enable efficientworkflows
• Create and manage prioritization efforts of sub-teams within the PBS group to ensure optimal portfolio progression and scientific rigor
• Develop the strategy for PBS to improve capacity and efficiency of platform technologies through innovation and application of new technologies, including automation, external capabilities and collaborations
• Leverage new technologies and existing bioanalytical approaches to characterize protein biologics and ADC mechanisms of action
• Work closely with Research and external departments to balance priorities between clinical-stage programs and pre-IND programs, with seamless transfer of knowledge and processes from research to the Pharmaceutical Sciences team
• Provide supervision and mentorship of individuals in team, establishing the technical vision, implementation of new technologies and enabling personal growth of team members
• Promote a culture of professionalism and collaboration focused on patient outcomes in alignment with company goals andvalues

BASIC QUALIFICATIONS

• in Biochemistry, Chemistry or related discipline
• Minimum 15 years post related oncology or chemistry experience in industry, including technical and scientific experience in drug discovery and preclinical development
• Expertise in ADC synthesis, including protein generation, small molecule synthesis, biochemical conjugation and in vitro and in vivo molecule stability characterization
• Deep experience building, leading and directly managing large teams, capable of giving feedback, coach, mentor, and developemployees
• Demonstrated track record in collaborative research in ADC Oncology drug discovery programs with strong business acumen and communication skills
• Ability to collaborate across teams and a variety of disciplines to create and communicate scientific strategy and priorities

PREFERRED QUALIFICATIONS

• Prior experience of scaling and process improvement in a high-throughput production environment, experience in lean six sigma a plus
• Strong track record of scientific accomplishments in industry as evidenced by publications or other equivalent achievements
• Experience getting results through creativity and unique problem solving
• A leader who uses data driven science and metrics to reinforce decision making

The annual base salary for this position ranges from $205, to $342, In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of of the base salary and eligibility to participate in our share based long term incentive program.

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments.

Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver / parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

Learn more at Pfizer Candidate Site - Benefits ( Pfizer compensation structures and benefit packages are aligned based on the location of hire.

The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and / or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.

These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure.

Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.

If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development