Translational Immunology - Academic Graduate Appointee
We have one opening for an Academic Graduate Appointee to support projects focused on developing novel nanoparticle-based vaccines against various bacterial and viral pathogens.
The candidate will work in a highly integrated environment as part of a multi-disciplinary team to develop, optimize, characterize, and validate nanoparticle-based vaccine formulations.
This position will include the production and characterization of protein antigens and nanoparticle constituents. This position is in the Biology and Biotechnology Division, Translational Immunology Group.
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In this role you will :
- Express, purify, and characterize proteins of high purity required for in vivo applications.
- Prepare, purify, and characterize nanoparticle platforms tailored for different vaccine formulations and vaccination routes.
- Use instrumentation to characterize purity, size, and homogeneity of biomolecules.
- Support routine immunological assays to assess vaccine formulations.
- Keep an accurate and detailed laboratory notebook and maintain complete records of experiments.
- Contribute to general lab maintenance, management of waste streams, and ordering / inventory of lab supplies.
- Compile data and protocols in Microsoft Office programs (Excel, Word, PowerPoint).
- Perform all assignments in accordance with ES&H, security, and business practice requirements and policies.
- Perform duties as assigned.
Minimum Qualifications :
- B.S. or B.A. in biological sciences or equivalent course work (within two years of application).
- Experience with aseptic technique, microbial cultures, and protein purification.
- Interpersonal and communication skills to effectively work in a team environment with a diverse technical staff.
- Strong attention to detail and ability to follow standard laboratory protocols and ES&H safety procedures.
- Experience using personal computers, Word, Excel, and PowerPoint applications.
Qualifications we desire :
- Experience with routine laboratory processes, including preparation of buffers.
- Experience working with gel electrophoresis, western blot, and other common molecular biology techniques.
- Experience with DNA extraction including minipreps, maxipreps, gel extraction, and PCR purification.
- Experience with culturing bacteria, including transformation and plating.
- Experience with liquid chromatography instrumentation.
- Experience with handling and characterizing proteins.
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