Modeling & Simulations Engineering Senior Scientist

Vertex Pharmaceuticals
Providence, Rhode Island, US
Full-time
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Modeling & Simulations Engineering Senior Scientist

Job Description

General Summary :

The M&S Engineering Senior Scientist will develop physical, mathematical and computational models based on structural mechanics, fluid dynamics, and thermodynamics.

The incumbent will generate mechanistic and data-driven insights that will accelerate design, manufacturing, and failure mode analysis of an immunoprotective device solution for cell and gene therapies.

Key Duties and Responsibilities :

  • Apply engineering skills, data analysis, computational modeling to optimize design and fabrication of an implantable combination product.
  • Manage complete modeling project operations entailing requirement gathering, scoping, input data requirements, problem solving, verification, validation, and documentation.
  • Initiate & lead brainstorming and ideation sessions to develop device design and manufacturing concepts.
  • Develop experimental designs in collaboration with other engineers and scientists.
  • Work with Device Fabrication team on assessing the manufacturability of the device designs via rapid prototyping methods and accelerate design ideation phase via fit-for-purpose models and simulations.
  • Collaborate with clinical and preclinical teams to understand anatomical constraints and eliminate device mechanical failure modes.
  • Effectively communicate modeling results and findings at multiple levels in the organization through project status meetings, presentations, and reports.

Knowledge and Skills :

  • Expertise in the mechanics and thermodynamics of polymers including plastics, hydrogels, and rubber materials.
  • Experience in multiphysics modeling of phase transition in engineering and biological materials.
  • Familiarity with implantable medical devices, and understanding of tissue mechanics.
  • Expertise in Computer Aided Design (e.g. SolidWorks), Finite Element Method (e.g. ANSYS Mechanical, or COMSOL), Finite Volumes Method (e.

g. Fluent, or Star-CCM+), and familiarity with scientific machine learning.

  • Excellent knowledge of mechanical engineering design concepts, ASTM standards, design control, and tolerance analysis with hands-on experience with materials test systems (i.e. Instron).
  • Quickly adapt to evolving priorities, rapidly acquire new skills, and stay informed on new methods and approaches.
  • Strong verbal and written communications skills with ability to effectively communicate at multiple levels in the organization through project status meetings, presentations, and reports.

Education and Experience :

Bachelor's degree and 8+ years of experience or a Master's degree and 5+ years of experience or a PhD and 2-5 years of experience, or the equivalent combination of education and experience.

Flex Designation :

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status :

In this Hybrid-Eligible role, you can choose to be designated as :

Before applying for this role, please read the following information about this opportunity found below.

1. Hybrid : work remotely up to two days per week; or select

2. On-Site : work five days per week on-site with ad hoc flexibility.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

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8 days ago
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