Senior Principal Scientist, Process Chemistry

Description

The purpose of this role is to provide process chemistry support to Phlow's Advanced Manufacturing R&D lab. The Senior Principal Scientist will possess an in-depth knowledge of process chemistry skills for the development of synthetic routes for drug substances. The candidate will perform multi-step chemical syntheses and product isolation / purification operations in the laboratory either independently or as part of a project team. The candidate will ensure excellence of our process development and technical transfer to Phlow's partners or customers. The candidate will personify Phlow's shared values and culture, both internally and externally. The candidate will work with the highest standards of safety, integrity, transparency, and ethics to create win-win scenarios for patients, customers, partners, and colleagues.

Requirements

Essential Job Duties & Responsibilities

• Provide process chemistry support to Phlow's Advanced Manufacturing R&D lab to ensure project deliverables are met on time and on budget.
• Independently design, synthesize, purify, and analyze chemical intermediates, target compounds, and impurities.
• Maintain accurate, legible, and complete records of all experiments and observations.
• Author progress reports and present scientific results to team members.
• Exhibit a high level of safety awareness and conduct lab operations in a safe manner.
• Contribute to the timely and accurate preparation of regulatory submissions.
• Participate in the ongoing continuous improvements in manufacturing processes resulting in improving product quality, robustness, and cost.
• Collaborate with Analytical Chemistry, EH&S, Engineering, Project Management, Quality Assurance and Regulatory Affairs to ensure strong working relationships with all partners and Phlow employees.

Experience & Qualifications

Preferred Qualifications

Physical Requirements