Title : Scientist
Location : North Chicago, IL
Pay : $30-37 / hr
Contract : 6+ months
Summary
Quantitative, Translational & ADME Sciences Department has an open position for a Scientist I position in North Chicago, IL.
The successful candidate will be responsible for non-regulated quantitative LC-MS / MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.
Key Responsibilities Include :
- Use liquid handling robotics.
- Perform quantitative LC-MS / MS (Liquid Chromatography Mass Spectrometry) analysis of small molecules from various bio-matrices in vivo and in vitro to support PK / PD, ADME, efficacy, and exploratory toxicology studies.
- Basic Operation and troubleshooting of AB Sciex LC-MS / MS systems.
- Maintain excellent documentation of all work including LIMS, test methods, and protocols.
- Work closely with multiple teams across Discovery and DMPK-BA to support bioanalysis.
Qualifications :
- B.S. in analytical chemistry or related field years of relevant academic / pharmaceutical industry experience.
- Knowledge of protein precipitation, liquid / liquid extraction, and solid phase extraction.
- Ability to operate and troubleshoot HPLCs, Leap / CTC PAL autosamplers and triple quad mass spectrometers.
- Experience with quantitative bioanalysis of small molecules.
- Knowledge of chromatographic and analytical methodologies.
- The ideal candidate is detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
- Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.
- Strong communication, interpersonal, and presentation skills.
- Experience operating and troubleshooting current LC-MS / MS platforms (Agilent HPLCs, Leap / CTC PAL and ADDA autosamplers, Sciex API-5500 / 6500 triple quad Mass Spectrometers) and software (e.
g. Discovery Quant, Analyst, Electronic notebook) is highly preferred.
Key Leadership Competencies :
- Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
- Learns fast, grasps the "essence" and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
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