High Throughput Antibody Characterization Scientist - Security Clearance Required

Company Description

Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States’ security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are committed to a diverse and equitable workforce with an inclusive culture that values and celebrates the diversity of our people, talents, ideas, experiences, and perspectives.

This is essential to innovation and creativity for continued success of the Laboratory’s mission.

Pay Range

$132,810 - $170,556 Annually

Please note that the pay range information is a general guideline only. Many factors are taken into consideration when setting starting pay including education, experience, the external labor market, and internal equity.

Job Description

We have an opening for a Staff Scientist in our high throughput antibody production and characterization team. This exciting opportunity is ideal for an experienced bench scientist proficient in high throughput antibody characterization.

You will be responsible for the development, implementation, and continuous optimization of automated high throughput screening platforms for the characterization of computationally designed therapeutic antibodies.

Our team values scientific excellence, innovation, diverse perspectives, and collaboration. Join our dynamic team of scientists dedicated to advancing biotechnology and making a significant impact on drug discovery and development.

You will

• Contribute to developing and implementing high throughput antibody characterization assays (e.g., BLI, SPR, capillary electrophoresis, DLS, DSF)
• Contribute to developing and implementing high throughput immunoassays (e.g., AlphaLISA, MSD, Gyros, Luminex, etc.)
• Analyze and interpret experimental data, troubleshoot technical issues, and propose innovative solutions
• Collaborate with cross-functional teams to support the generation of therapeutic antibodies for various drug discovery programs
• Maintain accurate and detailed laboratory records, write technical reports, and present findings to project teams and stakeholders
• Perform other duties as assigned

Qualifications

• B.S. degree or equivalent experience in biotechnology, biochemistry or a related scientific discipline
• Comprehensive hands-on experience in high throughput protein characterization techniques
• Proficiency with protein analytical techniques such as SDS-PAGE, Western blotting, ELISA or advanced immunoassay platforms (e.

g., AlphaLISA, MSD, Gyrolab, Luminex)

• Familiarity with protein characterization assays (e.g., SPR, BLI, capillary electrophoresis, DLS, DSF)
• Experience using automated liquid handling systems and LIMS
• Demonstrate ability to work effectively in a team environment and collaborate with colleagues from diverse scientific backgrounds
• Strong organizational skills, attention to detail, and ability to multitask in a fast-paced research environment.

Qualifications We Desire

• Design and execute experiments for high throughput antibody production and characterization using mammalian cell culture systems
• Increase efficiency of protein expression, purification, and characterization.
• Proficiency in molecular biology techniques, including gene cloning, transfection, and stable cell line generation
• Experience with antibody or other protein developability assessment.

Additional Information

All your information will be kept confidential according to EEO guidelines.

Position Information

This is a Flexible Term appointment, which is for a definite period not to exceed six years. If final candidate is a Career Indefinite employee, Career Indefinite status may be maintained (should funding allow).

Why Lawrence Livermore National Laboratory?

• Included in 2024 Best Places to Work by Glassdoor!
• Flexible Benefits Package
• 401(k)
• Relocation Assistance
• Education Reimbursement Program
• Flexible schedules (*depending on project needs)
• Inclusion, Diversity, Equity and Accountability (IDEA) - visit https : / / www.llnl.gov / diversity
• Our core beliefs - visit https : / / www.llnl.gov / diversity / our-values
• Employee engagement - visit https : / / www.llnl.gov / diversity / employee-engagement

Security Clearance

None required. However, if your assignment is longer than 179 days cumulatively within a calendar year, you must go through the Personal Identity Verification process.

This process includes completing an online background investigation form and receiving approval of the background check.

This process does not apply to foreign nationals.)

Pre-Employment Drug Test

External applicant(s) selected for this position must pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

Wireless and Medical Devices

Per the Department of Energy (DOE), Lawrence Livermore National Laboratory must meet certain restrictions with the use and / or possession of mobile devices in Limited Areas.

Depending on your job duties, you may be required to work in a Limited Area where you are not permitted to have a personal and / or laboratory mobile device in your possession.

This includes, but not limited to cell phones, tablets, fitness devices, wireless headphones, and other Bluetooth / wireless enabled devices.

If you use a medical device, which pairs with a mobile device, you must still follow the rules concerning the mobile device in individual sections within Limited Areas.

Sensitive Compartmented Information Facilities require separate approval. Hearing aids without wireless capabilities or wireless that has been disabled are allowed in Limited Areas, Secure Space and Transit / Buffer Space within buildings.

How to identify fake job advertisements

Please be aware of recruitment scams where people or entities are misusing the name of Lawrence Livermore National Laboratory (LLNL) to post fake job advertisements.

LLNL never extends an offer without a personal interview and will never charge a fee for joining our company. All current job openings are displayed on the Career Page under Find Your Job of our website.

If you have encountered a job posting or have been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond.

To learn more about recruitment scams : https : / / www.llnl.gov / sites / www / files / 2023-05 / LLNL-Job-Fraud-Statement-Updated-4.26.23.pdf

Equal Employment Opportunity

We are an equal opportunity employer that is committed to providing all with a work environment free of discrimination and harassment.

All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

We invite you to review the Equal Employment Opportunity posters which include EEO is the Law and Pay Transparency Nondiscrimination Provision .

Reasonable Accommodation

Our goal is to create an accessible and inclusive experience for all candidates applying and interviewing at the Laboratory.

If you need a reasonable accommodation during the application or the recruiting process, please use our online form to submit a request.

California Privacy Notice

The California Consumer Privacy Act (CCPA) grants privacy rights to all California residents. The law also entitles job applicants, employees, and non-employee workers to be notified of what personal information LLNL collects and for what purpose.

The Employee Privacy Notice can be accessed here .