Talent.com
Process Engineer III/ IV- Small Molecule/ Oligo/ Peptide
Process Engineer III/ IV- Small Molecule/ Oligo/ PeptideCRB • Denver, CO, US
Process Engineer III / IV- Small Molecule / Oligo / Peptide

Process Engineer III / IV- Small Molecule / Oligo / Peptide

CRB • Denver, CO, US
job_description.job_card.variable_days_ago
serp_jobs.job_preview.job_type
  • serp_jobs.job_card.full_time
job_description.job_card.job_description

Company Description

CRB is a leading provider of sustainable engineering, architecture, construction and consulting solutions to the global life sciences and food and beverage industries. Our more than 1,100 employees provide best-in-class solutions that drive success and positive change for our clients, our people and our communities. CRB is a privately held company with a rich history of serving clients throughout the world, consistently striving for the highest standard of technical knowledge, creativity and execution.

Job Description

We are seeking a skilled and experienced Process Engineer III / IV with deep expertise in small molecule manufacturing to join our engineering consulting team. This role combines technical leadership with strategic client engagement, supporting process design, scale-up, optimization, and regulatory compliance across a variety of pharmaceutical and chemical industry projects.

The Process Engineer III will lead the design and execution of process scopes—such as unit operations, systems, or facility areas—on small to medium-sized projects. You will manage scope, budget, and schedule, while maintaining clear communication with clients and internal teams. This role also includes mentoring junior staff, contributing to high-quality deliverables, and supporting capital project planning and regulatory alignment.

This position can be based near any CRB location

Key Responsibilities

  • Lead and support client projects focused on small molecule API process development, scale-up, and manufacturing optimization.
  • Conduct site assessments, gap analyses, and provide recommendations for process improvements and compliance.
  • Develop process flow diagrams (PFDs), piping and instrumentation diagrams (P&IDs), and mass / energy balances.
  • Translate client requirements into actionable design scope and document decisions, open issues, and action items.
  • Identify and escalate scope changes or design deviations to project leadership.
  • Collaborate with cross-functional teams including architecture, mechanical, electrical, and construction.
  • Prepare technical reports, proposals, and presentations for internal and client stakeholders.
  • Support capital project planning including feasibility studies, equipment selection, and facility design.
  • Ensure alignment with industry standards including cGMP, FDA, EMA, and ICH guidelines.
  • Participate in advanced project activities such as :

Technical bid tabulations

  • Vendor package management
  • Factory acceptance testing
  • Risk assessments (e.g., HAZOP, HACCP)
  • 3D model reviews and coordination
  • Sequence of operations and functional specification reviews
  • Mentor junior engineers and design staff.
  • Lead system design programming and planning with support from senior engineers.
  • Participate in cross-discipline squad checks and drive overall project quality.
  • Minimum Qualifications

  • Bachelor's or Master's degree in Chemical Engineering or a related discipline (ABET-accredited).
  • Minimum of 5 years of experience in small molecule process engineering, preferably in a consulting or client-facing role.
  • Strong understanding of chemical synthesis, purification, and formulation processes.
  • Experience in design firm or operating company settings within a related industry.
  • Strong written and verbal communication skills.
  • Intermediate experience with applicable industry and regulatory guidance and building codes.
  • Advanced technical knowledge and experience with small molecule API manufacturing equipment and utility systems, such as chemical reactors, filters, centrifuges, dryers, vacuum pumps, scrubbers, purified water, process compressed gases, and engineered heat transfer fluid systems.
  • Experience designing and implementing engineering controls for containment of highly potent APIs.
  • Experience with cGMP practices within regulated industries (FDA, EMA, JP, etc.).
  • Preferred Qualifications

  • EIT or PE certification.
  • Experience coordinating and managing design within project teams and with external partners.
  • Familiarity with commissioning, startup, qualification, and troubleshooting of process systems.
  • Experience with regulatory environments and validation documentation.
  • Prior experience in engineering consulting or client services.
  • Familiarity with process safety, risk assessments, and HAZOP studies.
  • Demonstrated experience leading a small team of process engineers on complex engineering design projects.
  • Compensation

    The pay range for a candidate selected for this position who is based in Denver is typically $103,125 to $165,000 annually. The base salary range represents the low and high end of the salary range for this position. The selected candidate's actual pay will be based on various factors, including but not limited to work location, qualifications, and relevant experience. In addition, CRB offers a total rewards package that includes comprehensive insurance coverage as well as the opportunity to participate in one or more annual incentive programs based on company and individual performance.

    Additional Information

    All your information will be kept confidential according to EEO guidelines.

    CRB is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity / Affirmative Action Employer and it is our policy to provide equal opportunity to all people without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, citizenship status, sex, sexual orientation, gender identity or any other legally protected category. Employment is contingent on background screening.

    CRB does not accept unsolicited resumes from search firms or agencies. Any resume submitted to any employee of CRB without a prior written search agreement will be considered unsolicited and the property of CRB. Please, no phone calls or emails.

    CRB offers a complete and competitive benefit package designed to meet individual and family needs.

    If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

    J-18808-Ljbffr

    serp_jobs.job_alerts.create_a_job

    Engineer Iv • Denver, CO, US

    Job_description.internal_linking.related_jobs
    Mechanical Process Engineer III

    Mechanical Process Engineer III

    Hunter Douglas, Inc. • Broomfield, CO, US
    serp_jobs.job_card.full_time
    Direct message the job poster from Hunter Douglas, Inc.Talent Acquisition Specialist @ Hunter Douglas | Full Cycle Recruiting. Hunter Douglas is the world's leading manufacturer of window coverings ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Process Utilities Engineer II

    Process Utilities Engineer II

    CRB • Denver, CO, US
    serp_jobs.job_card.full_time
    CRB is a leading provider of sustainable engineering, architecture, construction and consulting solutions to the global life sciences and food and beverage industries. Our more than 1,100 employees ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_hours • serp_jobs.job_card.promoted • serp_jobs.job_card.new
    Manufacturing Engineer III

    Manufacturing Engineer III

    York Space Systems LLC • Greenwood Village, CO, US
    serp_jobs.job_card.permanent
    York Space Systems was founded to radically improve spacecraft affordability and reliability, transforming next-generation space mission operations worldwide. As an innovative aerospace company, we ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Production Engineer II

    Production Engineer II

    QB Energy • Denver, CO, US
    serp_jobs.job_card.full_time
    The Production Engineer II will be responsible for a wide range of production engineering assignments—such as monitoring and optimizing production, designing artificial lift, recommending dow...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    R&D Engineer I

    R&D Engineer I

    CoorsTek, Inc. • Golden, CO, US
    serp_jobs.job_card.full_time
    Get AI-powered advice on this job and more exclusive features.It's exciting to work for a company that makes the world measurably better. We're committed to bringing safety, quality, and customer fo...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    MSAT Process SME III

    MSAT Process SME III

    Leiters Inc • Englewood, CO, US
    serp_jobs.job_card.full_time
    Manufacturing Science & Technology (MSAT) Process SME III.The Manufacturing, Sciences, and Technology (MSAT) Process SME will support GMP manufacturing operations. A Process SME is actively enga...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_hours • serp_jobs.job_card.promoted • serp_jobs.job_card.new
    Process Development Engineer I / II

    Process Development Engineer I / II

    Solid Power, Inc. • Brighton, CO, US
    serp_jobs.job_card.full_time
    Solid Power is seeking a Process Development Engineer to join our talented team working to revolutionize the battery industry through the development of next-generation, all solid-state rechargeabl...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Fabrication Process Engineer III

    Fabrication Process Engineer III

    Hunter Douglas • Broomfield, CO, US
    serp_jobs.job_card.full_time
    Hunter Douglas is the world's leading manufacturer of window coverings and a major manufacturer of architectural products. We are a brand that you know and trust.With more than 100 years of inno...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Process Development Engineer

    Process Development Engineer

    Gates Corporation • Englewood, CO, US
    serp_jobs.job_card.full_time
    Are you inspired by challenging the status quo? Do you thrive in collaborative environments that drive results? If so, Gates could be for you. Gates is a leading manufacturer of application-specific...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Controls Engineer II

    Controls Engineer II

    Forge Nano, Inc. • Brighton, CO, US
    serp_jobs.job_card.full_time
    Forge Nano seeks a Controls Engineer II to join their Engineering Design and Manufacturing Team, reporting to the Principal Engineer. This position will focus on developing the automation, logic, an...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Manufacturing Process Engineer III

    Manufacturing Process Engineer III

    Jobs via Dice • Broomfield, CO, US
    serp_jobs.job_card.full_time
    Process Engineer III role for a company specializing in high-quality window treatments.The position focuses on safe, efficient, and high-quality manufacturing by developing standard work procedures...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Sr. Liquid System Responsible Engineer IV - Lunar Permanence

    Sr. Liquid System Responsible Engineer IV - Lunar Permanence

    Blue Origin • Denver, CO, United States
    serp_jobs.job_card.permanent
    Applications will be accepted on an ongoing basis until the requisition is closed.At Blue Origin, we envision millions of people living and working in space for the benefit of Earth.We're working t...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Process Engineer

    Process Engineer

    STAQ Pharma Inc • Denver, CO, US
    serp_jobs.job_card.full_time
    The Process Engineer I will be part of our cross-functional team that continuously seeks to develop, improve, design and implement processes that meet or exceed our delivery, quality and cost expec...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Industrial Plant Engineer Manager III

    Industrial Plant Engineer Manager III

    Electra • Boulder, CO, US
    serp_jobs.job_card.full_time
    We're transforming one of the world's oldest industries with cutting-edge technology and an innovative approach.Backed by top-tier investors and recognized by Time as one of the "best Inventio...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Manufacturing Engineer II (Shift B) Temporary 6 months

    Manufacturing Engineer II (Shift B) Temporary 6 months

    Boston Scientific • Aurora, CO, US
    serp_jobs.job_card.full_time
    Diversity - Innovation - Caring - Global Collaboration - Winning Spirit- High Performance.At our company, we value diversity and believe it is our greatest strength. We are committed to empowering w...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Process Engineer (Energy / O&G)

    Process Engineer (Energy / O&G)

    Samuel Engineering, Inc. • Greenwood Village, CO, US
    serp_jobs.job_card.full_time
    Process Engineer (Energy / O&G).A Process Engineer will provide process development and engineering design expertise for oil and gas projects. Use advance knowledge and specialized training to dev...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Cost and Product Engineer II

    Cost and Product Engineer II

    CoorsTek, Inc. • Golden, CO, US
    serp_jobs.job_card.full_time
    It's exciting to work for a company that makes the world measurably better.We're committed to bringing safety, quality, and customer focus to the business of advanced ceramics manufacturing.Applyin...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_1_day • serp_jobs.job_card.promoted
    Sr Process Engineer

    Sr Process Engineer

    Kosmos • Denver, CO, US
    serp_jobs.job_card.permanent
    Growing Manufacturing Company in Butte, Montana has a need for a Process Engineer.This is a direct hire role with a full benefits package and relocation. Take responsibility for assigned projects fr...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted