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Vice President, Global Supply Chain

Vice President, Global Supply Chain

Revolution MedicinesSan Francisco, CA, United States
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Overview

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a member of the Revolution Medicines team, you will join colleagues in a commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

As we scale toward global commercialization, we are seeking a strategic and execution-oriented leader, Vice President, Global Supply Chain , reporting to the SVP of PDM , to lead our end-to-end supply chain operations across clinical and commercial programs. Reporting to the senior leadership within Pharmaceutical Development and Manufacturing (PDM), this role is responsible for building and optimizing a global, compliant, and scalable supply chain function — encompassing clinical trial material supply, commercial product readiness, procurement, manufacturing operations, planning, logistics, and distribution. The ideal candidate will have deep expertise in small molecule pharmaceutical operations, an understanding of the oncology development lifecycle, and the ability to thrive in a dynamic, fast-paced environment.

Responsibilities

  • Strategic Supply Chain Leadership

Develop and execute the global supply chain strategy to support late-stage development and commercial readiness, with emphasis on scalability, cost-efficiency, and regulatory compliance.

  • Serve as a key operational leader contributing to corporate planning, global launch strategies, and commercial supply chain buildout.
  • Partner with cross-functional stakeholders to influence senior leadership decisions on global supply chain strategy.
  • Clinical & Commercial Supply Management
  • Oversee supply of clinical trial materials across global studies in alignment with Clinical Operations, CMC, and Regulatory teams.

  • Lead commercialization planning and execution for late-stage assets, ensuring timely product availability and compliant distribution in the U.S. and ex-U.S. markets.
  • Manufacturing & External Network Oversight
  • Manage relationships with external manufacturing partners (CDMOs) across drug substance and drug product for small molecule assets.

  • Ensure capacity planning, tech transfer, and commercial-scale readiness in coordination with Technical Operations and Quality.
  • Global Planning, Logistics & Systems
  • Direct global demand forecasting, supply planning, and inventory strategies to support clinical and commercial needs.

  • Implement and enhance ERP and digital supply tools to improve visibility, analytics, and performance management.
  • Oversee global logistics, including cold chain handling if applicable.
  • Quality, Compliance & Risk Mitigation
  • Ensure supply chain operations comply with GMP / GDP and global regulatory requirements (e.g., FDA, EMA, DSCSA, FMD).

  • Proactively identify and mitigate risks across the supply chain, including business continuity planning and scenario modeling.
  • Team Leadership & Organizational Development
  • Build and lead a high-performing global supply chain organization, fostering collaboration, accountability, and operational excellence.

  • Define key performance metrics and drive continuous improvement across all supply chain functions.
  • Required Skills, Experience and Education

  • Minimum Bachelor’s degree in Supply Chain, Life Sciences, Engineering, or related field (MBA or advanced degree preferred).
  • 18+ years of progressive supply chain leadership, with strong experience in small molecule pharmaceuticals, including clinical and commercial supply.
  • Proven success building or scaling supply chain operations in a public, late-stage biotech or pharma company.
  • Deep understanding of GMP, GDP, and international regulatory expectations, with launch readiness experience in the U.S. and ex-U.S. markets.
  • Experience with outsourced manufacturing models and managing a global CDMO network.
  • Strong systems knowledge (e.g., NetSuite, SAP, Oracle) and familiarity with serialization, DSCSA, and global trade compliance.
  • Excellent leadership, communication, and cross-functional collaboration skills, particularly with Quality, Regulatory, CMC, Technical Operations, and Commercial functions.
  • Preferred Skills

  • Prior oncology supply chain experience, particularly with accelerated regulatory pathways.
  • Experience launching commercial products globally, including establishing third-party logistics (3PL) and distribution partners.
  • Knowledge of sustainability, ESG practices, and digital innovation in pharmaceutical supply chains.
  • Base Pay Salary Range

    The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

    Please note that base pay salary range is one part of the overall total rewards program at Revolution Medicines, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

    $284,000 — $355,000 USD

    Seniority level

  • Executive
  • Employment type

  • Full-time
  • Job function

  • Management and Manufacturing
  • Equal Opportunity

    Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity / expression, national origin / ancestry, age, disability, marital status, medical condition, and veteran status.

    Privacy

    Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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