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Principal Mechanical Engineer - Neuromodulation (Neurostimulators)
Principal Mechanical Engineer - Neuromodulation (Neurostimulators)Nevro • Audubon, PA, US
Principal Mechanical Engineer - Neuromodulation (Neurostimulators)

Principal Mechanical Engineer - Neuromodulation (Neurostimulators)

Nevro • Audubon, PA, US
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About Nevro

Nevro, now part of Globus Medical, is a global medical device company focused on improving the quality of life for patients with chronic pain. We developed and commercialized the Senza platform , including the Omnia™ and HFX iQ™ systems —the only spinal cord stimulators that deliver Nevro's proprietary HF10 therapy , a paresthesia-free, evidence-based treatment proven to reduce or eliminate opioid use in a majority of patients.

With HFX iQ , Nevro introduced a smart and adaptive stimulation platform , designed to personalize therapy based on real-time patient input and automatic optimization. Our neuromodulation systems continue to redefine what's possible in the treatment of chronic pain.

About the Role

We are seeking a Principal Mechanical Engineer to join our innovative R&D team focused on neuromodulation. You will be a technical leader responsible for the design, development, and verification of next-generation implantable Class III devices and their associated tools and systems. This role blends hands-on engineering with high-level design leadership, requiring expertise in miniaturization, biocompatible materials, and chronic-implant reliability.

You'll work across disciplines—including systems, electrical, clinical, and manufacturing—to bring smart, durable, patient-centric devices to life.

Key Responsibilities

Product Design & Architecture

  • Lead mechanical design of implantable pulse generators (IPGs), leads, surgical tools, and accessories.
  • Own product-level decisions on form factor, sealing, integration, and structural performance.
  • Apply best practices in DFM / DFX to balance functionality, usability, and manufacturability.

Materials & Processes

  • Select and qualify materials for chronic implantation (e.g., titanium, PEEK, silicone, polyimide, Pt / Ir).
  • Develop and refine assembly processes involving hermetic sealing laser welding overmolding , and adhesive bonding
  • Collaborate with suppliers and internal teams on microfabrication, metal forming, and cleanroom assembly.
  • Testing & Reliability

  • Define and execute verification testing for fatigue, vibration, drop, thermal cycling, fluid ingress, and long-term soak.
  • Lead root cause analysis and implement design mitigations for mechanical failure modes.
  • Contribute to the development of custom test methods, jigs, and accelerated aging protocols.
  • Documentation & Compliance

  • Generate engineering documentation in support of design controls (e.g., DHF, FMEA, test protocols, reports).
  • Participate in design reviews and risk analyses in compliance with FDA ISO 13485 , and IEC 60601 standards.
  • Drive and process ECOs and support regulatory submissions as needed.
  • Clinical & Cross-Functional Collaboration

  • Gather and integrate feedback from physicians, patients, and clinical staff to inform iterative product design.
  • Collaborate with systems engineering, electronics, software, and clinical teams to ensure robust product integration.
  • Communicate effectively across functions and present findings to senior management.
  • Leadership & Mentoring

  • Provide technical direction to cross-functional development teams.
  • Mentor junior engineers and support team growth through knowledge sharing and design leadership.
  • Qualifications

  • Bachelor's degree in Mechanical, Biomedical, or related Engineering field (MS or PhD preferred).
  • 8+ years of experience in medical device design, with at least 4 years focused on implantable Class III devices
  • Expertise in CAD (SolidWorks or similar), tolerance stack-ups, FEA, and GD&T.
  • Proven experience with biocompatible materials hermetic device design , and implantable reliability engineering
  • Familiarity with manufacturing methods like micro-welding, injection molding, and precision machining.
  • Strong understanding of medical device regulatory and quality standards (21 CFR 820, ISO 13485, ISO 14708, ISO 10993).
  • Demonstrated ability to lead by influence, drive complex programs, and thrive in a dynamic R&D environment.
  • Why Join Us?

    At Nevro, you'll help shape the future of neuromodulation—developing smart, patient-responsive devices that make a tangible difference in the lives of people living with chronic pain. As part of the Globus Medical family, we combine the scale and resources of a global medtech leader with the agility and innovation of a startup. If you're passionate about deeply technical work that truly matters, we'd love to talk.

    Target Pay Range

    The final starting salary offer to the successful candidate will be determined by evaluating several factors, such as education, experience, knowledge, skills, internal equity, alignment with market data, and geography.

  • Nevro is a multi-state employer, so the target pay range may increase or decrease depending on the city / state.
  • EEO Statement

    Nevro offers equal employment opportunity, regardless of race, color, creed, religion, national origin, marital or family status, sex, sexual orientation, gender expression (including religious dress and grooming practices), gender (including pregnancy, childbirth or medical condition related to pregnancy or childbirth), physical or mental condition, protected veteran status, disability, age or other characteristics protected by laws.

    1Senza HFX iQ™ uses a fixed set of instructions to provide optimized treatment recommendations that utilize direct patient input from assessments on pain and quality of life measures.

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    Principal Mechanical Engineer • Audubon, PA, US

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