Research Associate

Position Description

Cold Spring Harbor Laboratory is seeking a highly motivated Research Associate to join our dynamic and collaborative team. This position will be part of Dr. Peter Koo's Lab in the Department of Quantitative Biology and Dr. Kenneth Chang's Lab at the Functional Genomics Facility. The successful candidate will play a key role in conducting large-scale perturbation assays, including massively parallel reporter assays (MPRAs) and CRISPR interference (CRISPRi), to investigate the regulatory genomic elements (enhancers and promoters) that control gene expression across various cell types.

Position Responsibilities

• Conduct large-scale perturbation assays (MPRAs and CRISPRi) to study gene regulation.
• Collaborate with quantitative biologists and functional genomics scientists to design and implement experiments.
• Perform genome-scale screening techniques and contribute to high-complexity library constructions using various gene transfer technologies.
• Analyze and interpret data from perturbation screens, focusing on the relationship between regulatory elements and gene expression.
• Train and develop sequence-based deep neural networks to predict gene expression outcomes.
• Document findings and present results at lab meetings and conferences.
• Stay current with relevant literature and contribute to the lab's research goals.

Position Requirements

Education : PhD degree Molecular Biology, Genetics, Bioinformatics, or a related field is required.

Skills / Experience : Strong background in functional genomics, molecular biology techniques, and quantitative biology. Experience with CRISPR technology and high-throughput screening methods. Proficiency in data analysis and familiarity with computational tools and programming languages (e.g., Python, R). Excellent problem-solving skills and a passion for scientific research. Strong communication skills and the ability to work collaboratively in a multidisciplinary team.

Supplemental Information

How to Apply :

Join us in advancing our understanding of gene regulation and contributing to innovative research that impacts the field of quantitative biology and functional genomics! Please submit an online application here : Research Associate Position 01250. We look forward to reviewing your application.

Environment

Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program.

We believe that science is for everyone and our researchers have a wide variety of backgrounds.

Compensation and Benefits

Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our CSHL Benefits sites to learn more. The salary range for this role is $65,000-$80,000.00 The salary range and / or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and / or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).

CSHL is an EO Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor

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