Talent.com
Clinical Research Operations Director
Clinical Research Operations DirectorChronicleBio • San Francisco, CA, United States
Clinical Research Operations Director

Clinical Research Operations Director

ChronicleBio • San Francisco, CA, United States
job_description.job_card.variable_hours_ago
serp_jobs.job_preview.job_type
  • serp_jobs.job_card.full_time
job_description.job_card.job_description

1 day ago Be among the first 25 applicants

Chronicle Bio is a data-driven healthcare platform building the world’s most comprehensive biobank and multi-omic data resource for chronic conditions, starting with neuroimmune diseases. We work at the intersection of clinical research, biospecimen science, and AI to unlock transformative insights for precision medicine.

Overview

The Clinical Research Operations Director will oversee and coordinate operations across our multi-site Clinical Research enterprise. This role is responsible for ensuring compliance with all regulatory requirements, supporting the strategic growth of our research infrastructure, managing research and administrative staff, and together with the Clinical Trial Business Development Director, oversee budgets and financial performance. This position plays a critical role in advancing the organization’s mission to conduct high-quality, compliant, and innovative clinical research.

Key Responsibilities

Compliance & Regulatory Oversight

  • Ensure adherence to federal, state, and local regulations (FDA, OHRP, GCP, HIPAA, IRB, CLIA, etc.).
  • Maintain and monitor standard operating procedures (SOPs) across all sites.
  • Partner with clinical investigators and regulatory affairs to ensure timely protocol approvals, reporting, and audits.
  • Oversee research contracts, sub-investigator agreements, and compliance-related documentation across all sites.

Staff & Site Management

  • Supervise and mentor site-level Clinical Research Managers and Coordinators, nurses, and support staff.
  • Standardize processes, training, and performance management across all sites.
  • Foster a culture of accountability, teamwork, and continuous improvement.
  • Support recruitment and retention of clinical research staff across all sites.
  • Develop and manage budgets for clinical research operations across sites.
  • Deploy and enforce compliance with the CTMS platform across sites and coordinators.
  • Manage biobank operations across all sites including onboarding with ChronicleBio team and ensure compliance and quality around biospecimen management.
  • Monitor financial performance, including grant / contract billing, site budgets, and cost recovery.
  • Coordinate vendor and CRO relationships; oversee purchasing of equipment, supplies, and services.
  • Ensure effective resource allocation across all sites, balancing workload, staffing, and timelines.

    • Strategic Leadership & Growth

  • Collaborate with executive leadership to expand the clinical research enterprise nationally.
  • Contribute to strategic planning, new site onboarding, and process integration.
  • Implement standardized systems for data capture, reporting, and operational efficiency.
  • Serve as a liaison between investigators, external partners, and leadership.

    • Cross-Functional Collaboration

  • Partner closely with the Clinical Trial Business Development Director to operationalize new trial opportunities, ensuring rapid site activation, staffing readiness, and protocol compliance.
  • Provide operational input during trial feasibility and budget negotiations to align site capacity with business development goals.

    • Qualifications

    Education & Experience :

  • Bachelor’s degree in life sciences, healthcare administration, or related field required; Master’s degree preferred.
  • Minimum 7+ years of progressive experience in clinical research operations, preferably in an academic, healthcare, or multi-site research environment.
  • Demonstrated knowledge of clinical research regulations, compliance standards, and best practices.
  • Experience managing teams, budgets, and cross-functional operations.
  • Strong leadership, staff development, and interpersonal skills.
  • Excellent organizational and project management abilities.
  • Financial acumen with ability to manage budgets and contracts.
  • Proficiency with research management systems, CTMS, EHR integration, and related platforms.
  • Ability to thrive in a fast-paced, entrepreneurial environment with distributed teams.

    • Key Attributes

  • Mission-driven, with a passion for advancing clinical research to benefit patients.
  • Strategic thinker with strong operational execution.
  • Collaborative, adaptable, and able to balance detail with big-picture vision.
  • Position will start off remote and move to in-person early 2026

    • Details

  • Seniority level : Director
  • Employment type : Full-time
  • Job function : Management and Manufacturing

    • We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

    #J-18808-Ljbffr

    serp_jobs.job_alerts.create_a_job

    Director Research • San Francisco, CA, United States

    Job_description.internal_linking.related_jobs
    Associate Director, Clinical Operations

    Associate Director, Clinical Operations

    Corcept Therapeutics • Redwood City, CA, US
    serp_jobs.job_card.full_time
    Associate Director, Clinical Operations.Corcept is leading the way in the research and development of cortisol modulators, molecules that regulate cortisol activity at the glucocorticoid receptor (...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director of Clinical Operations

    Director of Clinical Operations

    EPM Scientific • San Francisco, CA, United States
    serp_jobs.job_card.full_time
    Director of Clinical Operations.A stealth-mode biotechnology company is pioneering a new class of immune medicines by decoding and directing the human immune system to combat cancer and autoimmune ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Associate Director, Clinical Operations- Biomarker & Bioanalytical Operations

    Associate Director, Clinical Operations- Biomarker & Bioanalytical Operations

    Gilead Sciences • San Francisco, CA, United States
    serp_jobs.job_card.full_time
    Associate Director, Clinical Operations - Biomarker & Bioanalytical Operations at Gilead Sciences.Lead biomarker and bioanalytical strategy within clinical operations to support Phase I–IV trials a...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Associate Director, Clinical Operations

    Associate Director, Clinical Operations

    Revolution Medicines • Redwood City, CA, US
    serp_jobs.job_card.full_time
    Associate Director, Clinical Operations.Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicte...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director, Health Research Operations

    Director, Health Research Operations

    Meta Platforms • Burlingame, CA, US
    serp_jobs.job_card.full_time
    Director, Health Research Operations.Meta's products give people the power to build community and bring the world closer together. The Meta Health team supports this mission in the discovery, develo...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Clinical Operations Associate Director (Biotechnology / Oncology)

    Clinical Operations Associate Director (Biotechnology / Oncology)

    Exelixis • Alameda, CA, United States
    serp_jobs.job_card.full_time
    The Clinical Operations Associate Director combines end-to-end design, execution, and reporting of oncology clinical trials with leadership in study teams and across matrix teams.This position is a...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director Clinical Operations

    Director Clinical Operations

    Clinical Resource Network (CRN) • San Francisco, CA, United States
    serp_jobs.job_card.full_time
    Clinical Resource Network (CRN).Our client is looking for a director to lead transformational clinical operations in a high-growth healthcare technology environment, directing a team of 200+ frontl...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Associate Director, Clinical Operations

    Associate Director, Clinical Operations

    Lyell Immunopharma • South San Francisco, CA, US
    serp_jobs.job_card.full_time
    Associate Director, Clinical Operations.Using living cells to treat and sometimes even cure cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies h...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director of Clinical Operations

    Director of Clinical Operations

    VirtualVocations • Concord, California, United States
    serp_jobs.job_card.full_time
    A company is looking for a Director of Clinical Services Operations.Key Responsibilities Lead day-to-day operations ensuring compliance with contracts and regulations Develop and implement proce...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director of Clinical Operations

    Director of Clinical Operations

    Fortvita Biologics • Palo Alto, CA, United States
    serp_jobs.job_card.full_time
    Fortvita Biologics is a biopharmaceutical company based in the San Francisco Bay Area specializing in antibody discovery and engineering, with platforms that span antibody-drug conjugates (ADCs), b...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Director of Clinical Operations

    Director of Clinical Operations

    Power • Fremont, CA, US
    serp_jobs.job_card.full_time
    At Power, we believe every patient should have easy access to clinical trials as a care option.Our platform connects patients to research opportunities quickly, transparently, and compassionately —...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director of Clinical Operations

    Director of Clinical Operations

    89bio Inc. • San Francisco, CA, United States
    serp_jobs.job_card.full_time
    Pegozafermin is a specifically engineered, potentially best-in-class fibroblast growth factor 21 (FGF21) analog with unique glycoPEGylated technology that optimizes biological activity through an e...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director, Clinical Operations

    Director, Clinical Operations

    Heartflow • San Francisco, CA, United States
    serp_jobs.job_card.full_time
    HeartFlow is a medical technology company advancing the diagnosis and management of coronary artery disease, using cutting-edge technology. The HeartFlow FFRCT Analysis provides a color-coded, 3D mo...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Associate Director, Clinical Operations- Biomarker & Bioanalytical Operations

    Associate Director, Clinical Operations- Biomarker & Bioanalytical Operations

    Gilead • San Mateo, CA, US
    serp_jobs.job_card.full_time
    At Gilead, we're creating a healthier world for all people.For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer working relentlessly to develop therapie...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Senior Director, Clinical Site Contracts & Budgets, Clinical Operations

    Senior Director, Clinical Site Contracts & Budgets, Clinical Operations

    Revolution Medicines • San Francisco, CA, United States
    serp_jobs.job_card.full_time
    Senior Director, Clinical Site Contracts & Budgets, Clinical Operations.Senior Director, Clinical Site Contracts & Budgets, Clinical Operations. Senior Director, Clinical Site Contracts & Budgets, C...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director, Clinical Operations

    Director, Clinical Operations

    Mirum Pharmaceuticals • San Mateo, CA, US
    serp_jobs.job_card.full_time
    Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases.We are passionate about advancing scientific discoveries to become important medicines ...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted
    Director, Clinical Operations

    Director, Clinical Operations

    Summit Therapeutics Sub, Inc. • Menlo Park, CA, United States
    serp_jobs.job_card.full_time
    Career Opportunities with Summit Therapeutics Sub, Inc.Careers At Summit Therapeutics Sub, Inc.Current job opportunities are posted here as they become available. Location : On-Site 4 days per week a...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_variable_days • serp_jobs.job_card.promoted
    Clinical Manager

    Clinical Manager

    Bass Surgery Center (11621) • WALNUT CREEK, California, United States
    serp_jobs.job_card.full_time
    Bass Surgery Center is hiring a Clinical Manager.Welcome to Bass Surgery Center,.ASC environment committed to producing the highest quality work and experience for patients and their families.Clini...serp_jobs.internal_linking.show_more
    serp_jobs.last_updated.last_updated_30 • serp_jobs.job_card.promoted