Associate Principal Scientist, Protein AnalyticsMSD Malaysia • Boston, MA, United States
Associate Principal Scientist, Protein Analytics
MSD Malaysia • Boston, MA, United States
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job_description.job_card.job_descriptionBroad experience in the characterization of proteins including biophysical and analytical techniques with focus on developability workflows Experience in advancing large molecule therapeutics through discovery pipelines Expertise in analytical method development, high throughput execution, and the application of new technologies Excellent oral and written communication skills, strong problem – solving and inter-personal skills, collaborative and self-motivated. Deep expertise in characterization of biologics using LC based methods including SEC, reverse phase chromatography, and hydrophobic interaction chromatography, including method development, validation and execution to support fast paced biologics discovery Hands on experience with LC / MS techniques for detailed characterization of biologics including mass determination, glycan-analysis, peptide mapping, and characterization of post-translational modifications. Demonstrated ability to work in a collaborative multi-disciplinary fast paced team environment. Excellent communication and organizational skills. Ability to multitask, to manage time, and prioritize activities to support and advance the pipeline. Experience with light scattering (SEC-MALS, DLS), thermal stability (DSF), and capillary electrophoresis-based methods (CE-SDS, cIEF) Experience with automated workflows, and high- throughput sample analyses Biologic program leadership experience Experience with EMPOWER and Signals / ELN is a plus Fluency in a modern programming language such as C++, Python, or similar. Experience with laboratory automation such as Tecan, Biomek, Hamilton, or similar. Prior management experience. Los Angeles Residents Only : We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
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