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Research Associate - Chem
Research Associate - ChemAltPep Corp. • Seattle, WA, US
Research Associate - Chem

Research Associate - Chem

AltPep Corp. • Seattle, WA, US
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Job Description

Job Description

Salary : $78,000 - $88,000 DOE

AltPep Corporation is a biomedical company based along Seattle's Lake Union developing groundbreaking disease-modifying treatments and detection tools for amyloid diseases by targeting a novel early molecular trigger : alpha sheet oligomers. Our lead programs focus on Alzheimers and Parkinsons diseases, with other amyloid diseases on the horizon. AltPeps goal is to change the course of these debilitating diseases that affect over a billion people around the globe.

AltPep draws its origins to Dr. Valerie Daggett's lab at the University of Washington's Bioengineering Department. We are looking for additional team members to join us at our state-of-the-art, headquarters located on the Eastside of Lake Union in Seattle.

About this Role

We are seeking a meticulous and dynamic Research Associate to join our team. You will be responsible for conducting and supporting laboratory research, including peptide synthesis, characterization (spectroscopy, biophysical, etc.), formulation activities, bioanalytical (pharmacokinetics) experiments, and stability studies, while ensuring the highest standards of quality and precision. Your contributions will be critical to the success of our research and development efforts, and you will have opportunities to work both independently and collaboratively within our innovative team.

What Youll Do :

  • Characterize peptides by UHPLC, mass spectrometry, circular dichroism, etc.
  • Engage in chemical synthesis and peptide modifications to meet research and development objectives.
  • Operate both manual and automated solid-phase peptide synthesis systems.
  • Conduct (prep- and semi-prep) HPLC purification of peptides.
  • Support novel Drug Product formulation development
  • Support bioanalytical experiments and stability studies
  • Troubleshoot and maintain instrumentation to ensure smooth laboratory operations.
  • Maintain rigorous quality of experimental details outlined in Standard Operating Procedures (SOPs).
  • Document research findings meticulously in lab books and records.
  • Work both independently and collaboratively within an innovative team to achieve project goals.
  • Prioritize and organize workflow to manage multiple tasks efficiently.
  • Maintain a clean and orderly laboratory environment.
  • Analyze and interpret data and generate reports
  • Regularly communicate results, in written form and oral presentations, to the rest of the team and occasionally to senior management and in All-Company meetings.

What You Bring : Must Haves :

  • Bachelor's degree in chemistry, chemical engineering, biochemistry, bioengineering, or a related field.
  • Experience in instrumental analysis using HPLC, UHPLC, and LC-MS.
  • Ability to conduct quantitative analysis and apply quality control criteria effectively.
  • Meticulous record-keeping abilities and attention to detail.
  • Flexibility to adapt to a fast-paced and dynamic work environment and responsiveness to quick changes in tasks / priorities.
  • Ability to learn rapidly and implement new laboratory techniques as needed
  • Strong organizational skills to manage multiple tasks and prioritize workflow.
  • What Will Separate You From the Rest :

  • 2+ years of post-graduate experience in a relevant field, with previous biotech experience being a plus.
  • Hands-on experience with solid-phase peptide synthesis and HPLC purification.
  • Experience with productivity and scientific software, including ChemDraw / Marvinsketch
  • Familiarity with PubMed and other information sources for pharmaceuticals.
  • Ability to work independently while also valuing team collaboration.
  • Knowledge of Quality Management Systems.
  • Ability to learn and implement new analytical and synthetic chemistry techniques.
  • Effective communication practices with peers and senior personnel.
  • Flexible approach to structure and workflow management.
  • Commitment to maintaining high standards of precision and cleanliness in laboratory work.
  • Debilitating diseases such as Alzheimer's and Parkinson's affect more than a billion people worldwide. Drawing upon decades of academic research, AltPep was founded to create groundbreaking tools to detect and treat such diseases. Although a young company, AltPep has been recognized for its scientific accomplishment and potential.

    While still small and nimble, we have grown to a team of thirty talented individuals dedicated to improving the lives of billions. We continue to grow and are looking for talented people to join the team and help us accomplish our mission.

    We offer competitive compensation to those joining our fight. The compensation range for a Research Associate is $78,000 - $88,000, depending on experience. AltPep takes care of its employees and offers generous stock options, medical, vision, and dental coverage for its employees and their dependents. We understand, and value, life outside of work and offer competitive PTO so you can rest and recharge.

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