Sr Project Manager, Clinical Development Operations

Project Manager

Iambic Therapeutics is seeking an experienced and detail-oriented Project Manager to join our team and lead integrated project management across clinical development functions, with primary responsibility for the Clinical Operations team. This role will work closely with all clinical development functions to manage and track clinical study timelines and deliverables from study start-up through execution. This position requires excellent project management skills, and the ability to coordinate complex activities across multiple workstreams and external partners. Experience in oncology drug development and familiarity with Clinical Operations is highly desirable.

The Sr. Project Manager of Clinical Development Operations will report to the Director of Clinical Operations and is based in San Diego, CA.

Key Responsibilities

• Lead planning, execution, and tracking of project timelines and deliverables to ensure alignment with program milestones and corporate goals.
• Manage relationships with third-party vendors (e.g., CROs), including oversight of scope, deliverables, timelines, and performance to ensure quality and accountability.
• Develop, integrate, and maintain detailed project plans across development workstreams, including scenario planning, resource forecasting, risk assessments, and budget tracking.
• Partner with the Clinical Operations team to develop, update, and track clinical study timelines and critical path activities from study start-up through execution.
• Facilitate internal and external team meetings by creating agendas, capturing meeting minutes and decisions, tracking action items, and ensuring timely follow-through.
• Maintain accurate project documentation, including status reports, risk registers, timelines, and meeting records.
• Monitor progress against project plans and proactively identify risks, delays, or resource gaps; lead or support development and implementation of mitigation strategies.
• Foster strong communication among Clinical Operations, Regulatory, Safety / Pharmacovigilance, Biostatistics, Data Management, CMC, and DMPK.

Qualifications

About Iambic Therapeutics

Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need.

Mission & Core Values

Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

Pay and Benefits

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the-art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.