Operations Director for Cryo-EM Core

Operations Director for Cryo-EM Core

Requisition # : A-141299-3

Status : Full Time

Type : Faculty

School : Zanvyl Krieger School of Arts and Sciences

Department / Program : Department of Biology

Location City : Baltimore

Location State : MD

Location Zip Code : 21218

Closing Date : Open until filled

To apply : General Description

General Description

The Johns Hopkins University invites applications for Operations Director of the Cryo-EM Core located on the Homewood Campus.

This is a full-time, non-tenure track position supported by the Krieger School of Arts and Sciences. The Cryo-EM Core houses instrumentation serving the diverse research interests of Johns Hopkins University.

The current scope of the Homewood cryo-EM facility includes : 1 Titan Krios, 1 Helios Hydra Bio (to be purchased), 1 Talos200, 1 T12, all sample preparation tools such as Vitrobot, and initial data storage / transfer and pre-processing capabilities.

The Operations Director of the Cryo-EM shared resource core at Johns Hopkins University (Homewood Campus) is responsible for the scientific and strategic oversight, as well as the implementation of state-of-the-art technologies for cryo-EM imaging, in support of research projects of a broad spectrum of faculty from our institution.

The Operations Director will interface closely with their counterpart, the Operations Director of the cryo-EM core at the School of Medicine Campus, to implement a world-class cryo-EM facility across Johns Hopkins campuses, which together will function as an integrated team, sharing expertise and support.

The Operations director will maintain a high level of professional expertise and scientific networking within the global cryo-EM community.

Responsibilities :

Implement and maintain state-of-the-art technologies and expertise on the Homewood campus that will support cryo-EM and cryo-ET data collection.

Ensure that all instrumentation and equipment operate efficiently and produce data of the highest possible quality. Maintain appropriate documentation for the shared resource.

Train users to become independent in sample preparation, microscope use, data collection, and initial pre-processing of data.

Create and implement educational programs that will serve the needs of the scientific user community and promote the scientific programs of the cryo-EM shared resource.

• Attract and retain outstanding research staff to support daily operations as needed.
• Supervise staff scientists to ensure the highest standards of microscope operation, data production and collaboration with lab members.
• Communicate ongoing progress to user groups and advisory committees and act as a key interface to engage new projects across the Johns Hopkins campuses.
• Integrate with the Operations Director and support staff at the cryo-EM facility at the Johns Hopkins School of Medicine to support each-other's technical and operational goals, ensuring that resources are accessible to all users across Hopkins.
• Participate in external funding applications, , large-scale Center grants and collaborative grant applications, which will be essential for the health of cryo-EM.

Provide support for Johns Hopkins investigators in obtaining preliminary data and writing grant applications aimed at obtaining research grants involving cryo-EM applications.

• Communicate with vendors about maintenance and upgrade of equipment as well as opportunities offered by new instrumentation, thus ensuring that the shared resource represents the state-of-the-art in cryo-EM.
• Work with leadership in the Departments of Biology and Biophysics, and the Krieger School of Arts and Sciences, in developing budgets and meeting financial expectations of the cryo-EM shared resource

Qualifications

Minimum Requirements :

Preferred Qualifications :

• Doctoral degree in biochemistry, biology, chemistry, physics, or a related field.
• Proficiency in utilizing Thermo Fisher Scientific microscopes and grid preparation tools, including Vitrobot, CP3-Plunger, and other associated instruments.
• Specialized knowledge in contemporary cryo-EM methodologies, encompassing data collection (EPU, Serial EM, or Leginon) and proficiency in various image processing software packages (Relion, cryoSPARC, EMAN2, cisTEM, Sphire).
• Previous involvement in structural biology, particularly in macromolecular model construction using tools such as Chimera and Coot, along with experience in employing structure validation tools.
• Exceptional technical acumen, effective communication skills, and a demonstrated ability in teaching.

Application Instructions

Applications should be submitted electronically to Interfolio

Candidates should include a cover letter describing their principal expertise and accomplishments, a complete resume, and the names and contact information for at least three references (two additional letters may be required at a later date).

To apply for this position, visit :

The Johns Hopkins University is committed to equal opportunity for its faculty, staff, and students. To that end, the university does not discriminate on the basis of sex, gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status or other legally protected characteristic.

The university is committed to providing qualified individuals access to all academic and employment programs, benefits and activities on the basis of demonstrated ability, performance and merit without regard to personal factors that are irrelevant to the program involved.

Pre-Employment Information

The successful candidate(s) for this position will be subject to a pre-employment background check.

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at jhurecruitment@ .

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Johns Hopkins has mandated COVID-19 and influenza vaccines, as applicable. The COVID-19 vaccine does not apply to positions located in the State of Florida.

Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons.

Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit and all other JHU applicants should visit .

The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly.

The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination.

This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing.

Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers.

Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.