Roles & Responsibilities :
- Independently plan, execute, analyze, and interpret in vitro and in vivo immunological assays that support the initiation and / or advancement of drug candidate projects
- Proactively evaluate new technologies and develop new assays to accelerate early-stage
discovery activities and / or enhance our understanding of disease mechanisms
- Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, protein engineering, chemistry, translational medicine, biomarker and clinical groups
- Presents research findings and recommendations to senior staff and contribute to
preparation of research reports, manuscripts, INDs, and patent filings
Education & Experience :
Master's degree with + years of experience, or Bachelor's degree with + years of
experience in immunology, immuno-oncology, cell biology, molecular biology, or
biochemistry in industry or academia.
Direct experience in research drug discovery and target identification / validation in oncology
or immuno-oncology is highly desirable.
- Strong understanding of immune cell biology, including T cell and myeloid cells.
- Proficiency in primary T-cell-based functional assays such as activation, proliferation and
cytotoxicity.
Experience in conducting and optimizing cell-based assays, as well as performing studies
to assess immune responses in human and animal models (including whole blood, PBMCs,
and various primary cell subsets).
Hands-on experience in general molecular and cell biology methods, including mammalian cell culture, multi-color flow cytometry, western blot, ELISA / Luminex / MSD, and CRISPR
technology.
- Attention to detail with excellent organizational and record keeping skills is a requirement
- Excellent communication and interpersonal skills are required.
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