Scientist, Antibody
Join a cutting-edge, clinical-stage precision immuno-oncology company focused on developing breakthrough treatments for solid tumors and hematological malignancies.
This full-time, permanent role offers the opportunity to contribute to the advancement of a leading program developed by renowned scientists from Dana Farber, MGH, the Broad, and MIT.
With over $120M raised from top-tier investors, the company is driving its clinical pipeline forward while expanding and validating novel therapeutic programs.
Job Summary :
We are seeking a talented scientist with expertise in antibody discovery, engineering, and characterization. Reporting to the Senior Director of Antibodies, the successful candidate will play a pivotal role in discovering and optimizing therapeutic antibodies.
This is a primarily lab-based position, with opportunities to collaborate on project teams, interact with CRO partners, and contribute to strategic decision-making.
Key Responsibilities :
- Design, construct, and screen antibody libraries to identify or optimize antibodies with desired properties.
- Conduct biophysical characterization of antibodies.
- Collaborate closely with the Biology group to accelerate program advancement.
- Present and communicate research findings in group and project meetings.
- Maintain thorough documentation of experimental work in electronic lab notebooks.
Qualifications & Education Requirements :
- BS with 5 years, MS with 3 years, or PhD in a relevant field (title will be based on experience).
- Proven hands-on experience with yeast display and / or phage display.
- Expertise in antibody affinity maturation, humanization, and related techniques.
- Skilled in antibody biophysical characterization methods such as ELISA, binding kinetics (Octet / SPR), flow cytometry, DSF, and more.
- Experience with alternative antibody formats like single-domain or bispecific antibodies is a plus.
- Strong knowledge of therapeutic antibody development.
- Ability to work independently, designing, executing, and troubleshooting experiments with minimal supervision.
- A collaborative team player with excellent verbal and written communication skills, capable of thriving in a fast-paced environment.
Additional Information :
Candidates must have the right to work in the U.S. and be available to start immediately.
Apply :
Please quote job reference 107530 in all correspondence.