Computational Biologist (Data Science)

JOB DESCRIPTION

Battelle delivers when others can’t. We conduct research and development, manage national laboratories, design and manufacture products and deliver critical services for our clients whether they are a multi-national corporation, a small start-up or a government agency.

We recognize and appreciate the value and contributions of individuals with diverse backgrounds and experiences and welcome all qualified individuals to apply.

Job Summary

We are currently seeking a Data Scientist II (Computational Systems Biologist) . This position will support a team located in Columbus, OH .

At Battelle, our Health Analytics division supports a wide range of clients including government agencies, academic institutions, and private industry in sectors such as healthcare, national defense, environmental science, transportation, and energy.

We are dedicated to solving complex challenges with innovative analytical approaches.

We are currently seeking a Data Scientist with a strong background in Computational Systems Biology. This role is crucial for integrating biology, bioinformatics, and computational modeling to predict changes in biological systems over time and under different conditions.

The insights gained will drive solutions to pressing health and environmental issues.

Responsibilities

• Computational analysis of large multi-omics datasets and mathematical modeling of complex biological systems, for example flux balance analysis.
• Working with standard metagenomic and RNASeq bioinformatic workflows.
• Working with high throughput scRNA-Seq, scATAC-Seq analysis using existing single cell analysis software like Seurat and established single cell pipelines.
• Working with high dimensional multivariate and multi-modal data using techniques like Canonical correlation analysis, co-inertia analysis, partial least square analysis, factor analysis etc.
• Using methods like principal component analysis, spectral decomposition, t-SNE, UMAP for data visualization and clustering techniques like k-means clustering, agglomerative hierarchical clustering, graph partitioning etc.

for cell type annotations.

• Participating in collaborative projects with other leading academic research and industry collaborators on computational analysis of high-dimensional, cell and molecular profiling data to advance precision microbiome efforts.
• Expertise in predictive pattern recognition applied to molecular profiling data and mathematical modeling of biological and disease processes, and demonstrable ability to interpret the output of such analyses in the microbiome-host context, are prerequisite.
• Perform analyses in a transparent manner and to clearly communicate analysis results and methods with collaborating researchers who may or not have computational backgrounds.

Key Qualifications

A Bachelor’s degree with at least 2 years of applied data science experience, or a Ph.D. OR a M.S. with relevant industry experience.

Degree must be in bioinformatics, biology, engineering, physics, computer science, mathematics, or a related scientific discipline.

• Expertise in predictive pattern recognition applied to molecular profiling data and mathematical modeling of biological and disease processes, and demonstrable ability to interpret the output of such analyses in the microbiome-host context, are prerequisite.
• Expertise in analysis, interpretation and applied computational research on large multivariate molecular profiling datasets.
• Experience analyzing large-scale human / other eukaryotic and microbiome molecular profile datasets (e.g., TCGA).
• Experience developing and integrating data and tools to distill knowledge from large datasets.
• Excellence in relevant programming languages (ideally Python and / or R)
• A track record demonstrating scientific creativity, collaboration, and independence
• Excellent written and oral communication skills

Preferred Qualifications

• Prefer Master’s or Ph.D. with 3 years of industry experience.
• Experience with mathematical modeling of dynamical biological systems at the level of gene regulation and microbial communities.
• Experience in machine learning and biostatistics.
• Experience with epigenetics systems biology and / or epigenetics bioinformatics.
• Experience running methylation and ChIP datasets.
• Experience in structural biology including experience in molecular dynamics simulation, docking using Rosetta, AlphaFold and other docking tools
• Currently possess a SECRET level clearance.

Benefits : Live an Extraordinary Life

We care about your well-being, not just on the job. Battelle offers comprehensive and competitive benefits to help you live your best life.

• Balance life through a compressed work schedule : Most of our team follows a flexible, compressed work schedule that allows for every other Friday off giving you a dedicated day to accomplish things in your personal life without using vacation time.
• Take time to recharge : You get paid time off to support work-life balance and keep motivated.
• Prioritize wellness : Stay healthy with medical, dental, and vision coverage with wellness incentives and benefits plus a variety of optional supplemental benefits.
• Better together : Coverage for partners, gender-affirming care and health support, and family formation support.
• Build your financial future : Build financial stability with an industry-leading 401(k) retirement savings plan. For most employees, we put in 5 percent whether you contribute or not, and match your contributions on top of that.
• Advance your education : Tuition assistance is available to pursue higher education.
• Flexible work arrangements : You have options for where you work and when you work.

A Work Environment Where You Succeed

For brilliant minds in science, technology, engineering and business operations, Battelle is the place to do the greatest good by solving humanity’s most pressing challenges and creating a safer, healthier and more secure world.

You will have the opportunity to thrive in a culture that inspires you to :

• Apply your talent to challenging and meaningful projects
• Receive select funding to pursue ideas in scientific and technological discovery
• Collaborate with world-class experts in an inclusive environment
• Nurture and develop the next generation of scientific leaders
• Give back to and improve our communities

Vaccinations & Safety Protocols

Battelle may require employees, based on job duties, work location, and / or its clients’ requirements to follow certain safety protocols and to be vaccinated against a variety of viruses, bacteria, and diseases as a condition of employment and continued employment and to provide documentation that they are fully vaccinated.

If applicable, Battelle will provide reasonable accommodations based on a qualified disability or medical condition through the Americans with Disabilities Act or the Rehabilitation Act or for a sincerely held religious belief under Title VII of the Civil Rights Act of 1964 (and related state laws).

Battelle is an equal opportunity employer. We provide employment and opportunities for advancement, compensation, training, and growth according to individual merit, without regard to race, color, religion, sex (including pregnancy), national origin, sexual orientation, gender identity or expression, marital status, age, genetic information, disability, veteran-status veteran or military status, or any other characteristic protected under applicable Federal, state, or local law.

Our goal is for each staff member to have the opportunity to grow to the limits of their abilities and to achieve personal and organizational objectives.

We will support positive programs for equal treatment of all staff and full utilization of all qualified employees at all levels within Battelle.

The above statements are intended to describe the nature and level of work being performed by people assigned to this job.

They are not intended to be an exhaustive list of all responsibilities, activities and skills required of staff members.

No statement herein is intended to imply any authorities to commit Battelle unless special written permission is granted by Battelle's Legal Department.